Production and bioactivity of oligosaccharides derived from lactose

In an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological production...

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Detalles Bibliográficos
Autores: Villamiel, Mar, Montilla, Antonia, Olano, Agustín, Corzo, Nieves
Tipo de recurso: otro
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/126743
Acceso en línea:http://hdl.handle.net/10261/126743
Access Level:acceso abierto
Palabra clave:Prebiotic properties
Lactulosucrose
1-galactosyl lactulose
6′-galactosyl lactulose
Galactooligosaccharides
Lactose derivatives
Chemical and enzymatic isomerisation
Transglycosylation
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spelling Production and bioactivity of oligosaccharides derived from lactoseVillamiel, MarMontilla, AntoniaOlano, AgustínCorzo, NievesPrebiotic propertiesLactulosucrose1-galactosyl lactulose6′-galactosyl lactuloseGalactooligosaccharidesLactose derivativesChemical and enzymatic isomerisationTransglycosylationIn an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological productions of tagatose, lactulose, lactosucrose, lactulosucrose, and galactooligosaccharides, among others, have been described. Moreover, their main uses, based on their bioactivity and techno-functional properties, are also shown together with a brief description of purification methods of the mixtures obtained. Particular attention has been paid to a new generation of oligosaccharides derived from lactulose with a potential prebiotic effect, which is even better than that of this recognised functional ingredient. These novel oligosaccharides, mainly composed of 6′-galactosyl lactulose and 1-galactosyl lactulose, can be obtained with good yields either by transgalactosylation of lactulose or by chemical isomerisation under basic media of galactooligosaccharides—the latter constitutes a good and economic option.This work has been financed by projects AGL2011–27884 from MICINN, R + D program of the Comunidad de Madrid, project ALIBIRD-CM-P 2009/AGR-1469 and POII10–0178–4685 from Junta de Comunidades de Castilla-La Mancha and European regional development fund (ERDF)Peer ReviewedWiley-BlackwellComunidad de MadridMinisterio de Ciencia e Innovación (España)Junta de Comunidades de Castilla-La ManchaEuropean CommissionConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2015201520142015info:eu-repo/semantics/otherhttp://purl.org/coar/resource_type/c_3248Postprintinfo:eu-repo/semantics/acceptedVersioninfo:eu-repo/semantics/bookParthttp://hdl.handle.net/10261/126743reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#S2009/AGR-1469/ALIBIRDhttps://doi.org/10.1002/9781118817360.ch9Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1267432026-05-22T06:33:51Z
dc.title.none.fl_str_mv Production and bioactivity of oligosaccharides derived from lactose
title Production and bioactivity of oligosaccharides derived from lactose
spellingShingle Production and bioactivity of oligosaccharides derived from lactose
Villamiel, Mar
Prebiotic properties
Lactulosucrose
1-galactosyl lactulose
6′-galactosyl lactulose
Galactooligosaccharides
Lactose derivatives
Chemical and enzymatic isomerisation
Transglycosylation
title_short Production and bioactivity of oligosaccharides derived from lactose
title_full Production and bioactivity of oligosaccharides derived from lactose
title_fullStr Production and bioactivity of oligosaccharides derived from lactose
title_full_unstemmed Production and bioactivity of oligosaccharides derived from lactose
title_sort Production and bioactivity of oligosaccharides derived from lactose
dc.creator.none.fl_str_mv Villamiel, Mar
Montilla, Antonia
Olano, Agustín
Corzo, Nieves
author Villamiel, Mar
author_facet Villamiel, Mar
Montilla, Antonia
Olano, Agustín
Corzo, Nieves
author_role author
author2 Montilla, Antonia
Olano, Agustín
Corzo, Nieves
author2_role author
author
author
dc.contributor.none.fl_str_mv Comunidad de Madrid
Ministerio de Ciencia e Innovación (España)
Junta de Comunidades de Castilla-La Mancha
European Commission
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Prebiotic properties
Lactulosucrose
1-galactosyl lactulose
6′-galactosyl lactulose
Galactooligosaccharides
Lactose derivatives
Chemical and enzymatic isomerisation
Transglycosylation
topic Prebiotic properties
Lactulosucrose
1-galactosyl lactulose
6′-galactosyl lactulose
Galactooligosaccharides
Lactose derivatives
Chemical and enzymatic isomerisation
Transglycosylation
description In an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological productions of tagatose, lactulose, lactosucrose, lactulosucrose, and galactooligosaccharides, among others, have been described. Moreover, their main uses, based on their bioactivity and techno-functional properties, are also shown together with a brief description of purification methods of the mixtures obtained. Particular attention has been paid to a new generation of oligosaccharides derived from lactulose with a potential prebiotic effect, which is even better than that of this recognised functional ingredient. These novel oligosaccharides, mainly composed of 6′-galactosyl lactulose and 1-galactosyl lactulose, can be obtained with good yields either by transgalactosylation of lactulose or by chemical isomerisation under basic media of galactooligosaccharides—the latter constitutes a good and economic option.
publishDate 2014
dc.date.none.fl_str_mv 2014
2015
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/other
http://purl.org/coar/resource_type/c_3248
Postprint
info:eu-repo/semantics/acceptedVersion
dc.type.openaire.fl_str_mv info:eu-repo/semantics/bookPart
format other
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/126743
url http://hdl.handle.net/10261/126743
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
S2009/AGR-1469/ALIBIRD
https://doi.org/10.1002/9781118817360.ch9
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley-Blackwell
publisher.none.fl_str_mv Wiley-Blackwell
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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