Production and bioactivity of oligosaccharides derived from lactose

In an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological production...

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Detalles Bibliográficos
Autores: Villamiel, Mar, Montilla, Antonia, Olano, Agustín, Corzo, Nieves
Tipo de recurso: otro
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/126743
Acceso en línea:http://hdl.handle.net/10261/126743
Access Level:acceso abierto
Palabra clave:Prebiotic properties
Lactulosucrose
1-galactosyl lactulose
6′-galactosyl lactulose
Galactooligosaccharides
Lactose derivatives
Chemical and enzymatic isomerisation
Transglycosylation
Descripción
Sumario:In an attempt to offer a broad overview on lactose applications as a source of bioactive carbohydrates, in this chapter, the authors have collected the most recent investigations on methods to produce these compounds, which have a positive effect on gut microbiota. Chemical and biological productions of tagatose, lactulose, lactosucrose, lactulosucrose, and galactooligosaccharides, among others, have been described. Moreover, their main uses, based on their bioactivity and techno-functional properties, are also shown together with a brief description of purification methods of the mixtures obtained. Particular attention has been paid to a new generation of oligosaccharides derived from lactulose with a potential prebiotic effect, which is even better than that of this recognised functional ingredient. These novel oligosaccharides, mainly composed of 6′-galactosyl lactulose and 1-galactosyl lactulose, can be obtained with good yields either by transgalactosylation of lactulose or by chemical isomerisation under basic media of galactooligosaccharides—the latter constitutes a good and economic option.