HR and chromatin assembly requirements for RFA1-MN cell viability in the absence and presence of calcium

figure posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado (A, C, and D) Effect of the indicated mutations in the growth of RFA1-MN cells as determined by spotting 10-fold...

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Detalles Bibliográficos
Autores: Amiama-Roig, Ana, Barrientos-Moreno, Marta, Cruz-Zambrano, Esther, López-Ruiz, Luz M., González-Prieto, Román, Ríos-Orelogio, Gabriel, Prado, Félix
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/391865
Acceso en línea:http://hdl.handle.net/10261/391865
https://digital.csic.es/handle/10261/391851
Access Level:acceso abierto
Palabra clave:sister chromatid cohesion
core homologous recombination
active origins facilitates
Descripción
Sumario:figure posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado (A, C, and D) Effect of the indicated mutations in the growth of RFA1-MN cells as determined by spotting 10-fold serial dilutions of the same number of mid-log growing cells onto SMM medium without or with the indicated concentrations of CaCl2. (B) DSB sensitivity of rtt105∆ cells to HO-induced DSBs, as determined by spotting 10-fold serial dilutions of the same number of mid-log growing cells. Cells were transformed with pGAL-HO and grown in glucose (GAL1p repression) and galactose-containing medium (GAL1p activation). Wild-type and rad52∆ cells were included as control. The analyses were repeated at least twice with similar results. Mutants scored in the SGA screening are shown in bold.