Metal-Catalyzed annulations through activation and cleavage of C−H bonds

The exponential increase in the number of catalytic transformations that involve a metal-promoted activation of hitherto considered inert C−H bonds is promoting a fundamental change in the field of synthetic chemistry. Although most reactions involving C−H activations consist of simple functionaliza...

Descripción completa

Detalles Bibliográficos
Autores: Gulías Costa, Moisés, Mascareñas Cid, José Luis
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/14870
Acceso en línea:http://hdl.handle.net/10347/14870
Access Level:acceso abierto
Palabra clave:Materias::Investigación::23 Química::2302 Bioquímica
Descripción
Sumario:The exponential increase in the number of catalytic transformations that involve a metal-promoted activation of hitherto considered inert C−H bonds is promoting a fundamental change in the field of synthetic chemistry. Although most reactions involving C−H activations consist of simple functionalizations or additions, recent years have witnessed an upsurge in related transformations that can be formally considered as cycloaddition processes. These transformations are particularly appealing from a synthetic perspective because they allow the conversion of readily available substrates into highly valuable cyclic products in a rapid and sustainable manner. In many cases, these annulations involve the formation of metallacyclic intermediates that resemble those proposed for standard metal-catalyzed cycloadditions of unsaturated precursors

Similares en LA Referencia