Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression

Supplemental Materials and Methods includes detailed information about transgenes and CRISPR allele generation. -- Supplemental Table S1 includes all the C. elegans strains used in this study. -- Supplemental Figure S1 related to Figure 1, shows the evolutionary history of the CASP/CUX locus. -- Sup...

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Detalles Bibliográficos
Autores: Leyva-Díaz, Eduardo, Cesar, Michael, Pe, Karinna, Jordá-Llorens, José Ignacio, Valdivia, Jessica, Hobert, Oliver
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/385670
Acceso en línea:http://hdl.handle.net/10261/385670
Access Level:acceso abierto
Palabra clave:C. elegans
Alternative splicing
Homeobox
Neuronal cell fate
Pan-neuronal gene expression
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spelling Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expressionLeyva-Díaz, EduardoCesar, MichaelPe, KarinnaJordá-Llorens, José IgnacioValdivia, JessicaHobert, OliverC. elegansAlternative splicingHomeoboxNeuronal cell fatePan-neuronal gene expressionSupplemental Materials and Methods includes detailed information about transgenes and CRISPR allele generation. -- Supplemental Table S1 includes all the C. elegans strains used in this study. -- Supplemental Figure S1 related to Figure 1, shows the evolutionary history of the CASP/CUX locus. -- Supplemental Figure S2 related to Figure 2, shows the characterization of cone-1/CASP mutants. -- Supplemental Figure S3 related to Figure 3, shows CEH-44/CUX protein structure and sequence details. -- Supplemental Figure S4 related to Figure 4, shows the expression analysis of an endogenous cone-1/CASP transcriptional reporter. -- Supplemental Figure S5 related to Figure 5, shows the characterization of new unc-75/CELF reporter and null alleles. -- Supplemental Figure S6 related to Figure 5, shows a more extensive schematic of the findings of this work. -- Supplemental Table 1 provides a list of strains used in this study.Peer reviewedCold Spring Harbor Laboratory PressConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520252025info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1application/docxhttp://hdl.handle.net/10261/385670reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésLeyva-Díaz, Eduardo; Cesar, Michael; Pe, Karinna; Jordá-Llorens, José Ignacio; Valdivia, Jessica; Hobert, Oliver. Alternative splicing controls pan-neuronal homeobox gene expresión. http://dx.doi.org/10.1101/gad.352184.124. http://hdl.handle.net/10261/385552http://dx.doi.org/10.1101/gad.352184.124Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3856702026-05-22T06:33:51Z
dc.title.none.fl_str_mv Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
title Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
spellingShingle Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
Leyva-Díaz, Eduardo
C. elegans
Alternative splicing
Homeobox
Neuronal cell fate
Pan-neuronal gene expression
title_short Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
title_full Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
title_fullStr Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
title_full_unstemmed Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
title_sort Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression
dc.creator.none.fl_str_mv Leyva-Díaz, Eduardo
Cesar, Michael
Pe, Karinna
Jordá-Llorens, José Ignacio
Valdivia, Jessica
Hobert, Oliver
author Leyva-Díaz, Eduardo
author_facet Leyva-Díaz, Eduardo
Cesar, Michael
Pe, Karinna
Jordá-Llorens, José Ignacio
Valdivia, Jessica
Hobert, Oliver
author_role author
author2 Cesar, Michael
Pe, Karinna
Jordá-Llorens, José Ignacio
Valdivia, Jessica
Hobert, Oliver
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv C. elegans
Alternative splicing
Homeobox
Neuronal cell fate
Pan-neuronal gene expression
topic C. elegans
Alternative splicing
Homeobox
Neuronal cell fate
Pan-neuronal gene expression
description Supplemental Materials and Methods includes detailed information about transgenes and CRISPR allele generation. -- Supplemental Table S1 includes all the C. elegans strains used in this study. -- Supplemental Figure S1 related to Figure 1, shows the evolutionary history of the CASP/CUX locus. -- Supplemental Figure S2 related to Figure 2, shows the characterization of cone-1/CASP mutants. -- Supplemental Figure S3 related to Figure 3, shows CEH-44/CUX protein structure and sequence details. -- Supplemental Figure S4 related to Figure 4, shows the expression analysis of an endogenous cone-1/CASP transcriptional reporter. -- Supplemental Figure S5 related to Figure 5, shows the characterization of new unc-75/CELF reporter and null alleles. -- Supplemental Figure S6 related to Figure 5, shows a more extensive schematic of the findings of this work. -- Supplemental Table 1 provides a list of strains used in this study.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
format dataset
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/385670
url http://hdl.handle.net/10261/385670
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Leyva-Díaz, Eduardo; Cesar, Michael; Pe, Karinna; Jordá-Llorens, José Ignacio; Valdivia, Jessica; Hobert, Oliver. Alternative splicing controls pan-neuronal homeobox gene expresión. http://dx.doi.org/10.1101/gad.352184.124. http://hdl.handle.net/10261/385552
http://dx.doi.org/10.1101/gad.352184.124

dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/docx
dc.publisher.none.fl_str_mv Cold Spring Harbor Laboratory Press
publisher.none.fl_str_mv Cold Spring Harbor Laboratory Press
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
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