Supplemental material: Alternative splicing controls pan-neuronal homeobox gene expression

Supplemental Materials and Methods includes detailed information about transgenes and CRISPR allele generation. -- Supplemental Table S1 includes all the C. elegans strains used in this study. -- Supplemental Figure S1 related to Figure 1, shows the evolutionary history of the CASP/CUX locus. -- Sup...

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Detalles Bibliográficos
Autores: Leyva-Díaz, Eduardo, Cesar, Michael, Pe, Karinna, Jordá-Llorens, José Ignacio, Valdivia, Jessica, Hobert, Oliver
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/385670
Acceso en línea:http://hdl.handle.net/10261/385670
Access Level:acceso abierto
Palabra clave:C. elegans
Alternative splicing
Homeobox
Neuronal cell fate
Pan-neuronal gene expression
Descripción
Sumario:Supplemental Materials and Methods includes detailed information about transgenes and CRISPR allele generation. -- Supplemental Table S1 includes all the C. elegans strains used in this study. -- Supplemental Figure S1 related to Figure 1, shows the evolutionary history of the CASP/CUX locus. -- Supplemental Figure S2 related to Figure 2, shows the characterization of cone-1/CASP mutants. -- Supplemental Figure S3 related to Figure 3, shows CEH-44/CUX protein structure and sequence details. -- Supplemental Figure S4 related to Figure 4, shows the expression analysis of an endogenous cone-1/CASP transcriptional reporter. -- Supplemental Figure S5 related to Figure 5, shows the characterization of new unc-75/CELF reporter and null alleles. -- Supplemental Figure S6 related to Figure 5, shows a more extensive schematic of the findings of this work. -- Supplemental Table 1 provides a list of strains used in this study.