The Pathophysiology of Portal Vein Thrombosis in Cirrhosis: Getting Deeper into Virchows Triad
Portal vein thrombosis (PVT) is a common complication among patients with cirrhosis. However, its pathophysiology is not well established and there are currently very few predictive factors, none of which are actually useful, from a clinical perspective. The contribution of each of the vertices of V...
| Autores: | , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2022 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositório: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/185770 |
| Acesso em linha: | https://hdl.handle.net/2445/185770 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Cirrosi hepàtica Coagulació sanguínia Trombosi Endoteli Vena porta Circulació sanguínia Hepatic cirrhosis Blood coagulation Thrombosis Endothelium Portal vein Circulation of the blood |
| Resumo: | Portal vein thrombosis (PVT) is a common complication among patients with cirrhosis. However, its pathophysiology is not well established and there are currently very few predictive factors, none of which are actually useful, from a clinical perspective. The contribution of each of the vertices of Virchow's triad, e.g., blood hypercoagulability, blood flow, and portal vein endothelial damage in the development of PVT is not clear. In this review, we aim to recapitulate the latest studies on the field of PVT development in order to understand its mechanisms and discuss some of the future directions in the study of this important complication of cirrhosis. |
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