Pru p 3‐Epitope‐based sublingual immunotherapy in a murine model for the treatment of peach allergy
[Scope] Food‐specific immunotherapy (SIT) is a promising treatment for lipid transfer protein (LTP)‐syndrome. We propose a novel sublingual‐SIT (SLIT) that combines a Pru p 3 T‐cell peptide and an oligodeoxyribonucleotide (ODN) with CpG motifs (ODN‐CpG) as adjuvants to induce a specific Th1/Treg res...
| Autores: | , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/190522 |
| Acceso en línea: | http://hdl.handle.net/10261/190522 |
| Access Level: | acceso abierto |
| Palabra clave: | Anaphylaxis Food‐allergy Lipid transfer protein Mouse model Sublingual immunotherapy |
| Sumario: | [Scope] Food‐specific immunotherapy (SIT) is a promising treatment for lipid transfer protein (LTP)‐syndrome. We propose a novel sublingual‐SIT (SLIT) that combines a Pru p 3 T‐cell peptide and an oligodeoxyribonucleotide (ODN) with CpG motifs (ODN‐CpG) as adjuvants to induce a specific Th1/Treg response. |
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