Synthesis of a New Conformationally Constrained Glycoamino Acid Building Block

The synthesis of a suitably protected β-D-glucopyranosyl-(S)-α-methylserine derivative - a new conformationally constrained glycosylated quaternary amino acid analogue of β-D-glucopyranosyl-L-serine - is described. This compound can be used as an attractive building block for the synthesis of new, c...

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Bibliographic Details
Authors: Avenoza, A. [0000-0002-5465-3555], Peregrina, J.M. [0000-0003-3778-7065], San Martín, E.
Format: article
Status:Published version
Publication Date:2003
Country:España
Institution:Universidad de La Rioja (UR)
Repository:RIUR. Repositorio Institucional de la Universidad de La Rioja
OAI Identifier:oai:portal.dialnet.es:doc/5bbc690cb750603269e8141b
Online Access:https://investigacion.unirioja.es/documentos/5bbc690cb750603269e8141b
Access Level:Open access
Keyword:Amino acids and derivatives
Azides
Glycosidation
Peptide analogues/mimetics
Description
Summary:The synthesis of a suitably protected β-D-glucopyranosyl-(S)-α-methylserine derivative - a new conformationally constrained glycosylated quaternary amino acid analogue of β-D-glucopyranosyl-L-serine - is described. This compound can be used as an attractive building block for the synthesis of new, constrained glycopeptides. © 2003 Elsevier Ltd. All rights reserved.