Conformational promiscuity in triazolamers derived from quaternary amino acids mimics peptide behaviour

1,4-Substituted triazole oligomers made from quaternary amino acid derivatives present a conformational behaviour with similarities to that of natural peptides. Twisted strand and zig-zag type conformations have both been obtained in the crystal state. In a solution signs of weakly ordered structure...

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Detalles Bibliográficos
Autores: Solà Oller, Jordi, Bolte, Michael, Alfonso, Ignacio
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/128330
Acceso en línea:http://hdl.handle.net/10261/128330
Access Level:acceso abierto
Palabra clave:Peptides
Amino acid derivatives
Crystal state
Natural peptide
Ordered structures
Zig-zag
Descripción
Sumario:1,4-Substituted triazole oligomers made from quaternary amino acid derivatives present a conformational behaviour with similarities to that of natural peptides. Twisted strand and zig-zag type conformations have both been obtained in the crystal state. In a solution signs of weakly ordered structures have been detected depending on the substituents and the solvents used.