Influence of the severity of osteogenesis imperfecta on cranial measurements

Osteogenesis Imperfecta (OI) is a disease that causes bone fragility and deformities, affecting both the cranial base and the craniocervical junction, and may lead to other neurological disorders. A retrospective cross-sectional study was carried out based on cephalometric analysis of the cranial ba...

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Detalles Bibliográficos
Autores: Nova García, Manuel Joaquín De, García de Sola, Rafael, Burgueño Torres, Laura
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/102325
Acceso en línea:https://hdl.handle.net/20.500.14352/102325
Access Level:acceso abierto
Palabra clave:616.314-053.2
616.71
615.849
Osteogenesis imperfecta
Basilar invagination
Cranial base
Craniocervical junction
Platybasia
Ciencias Biomédicas
Odontología (Medicina)
Odontología infantil
Diagnóstico por imagen y medicina nuclear
32 Ciencias Médicas
3207.14 Osteopatología
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oai_identifier_str oai:docta.ucm.es:20.500.14352/102325
network_acronym_str ES
network_name_str España
repository_id_str
spelling Influence of the severity of osteogenesis imperfecta on cranial measurementsNova García, Manuel Joaquín DeGarcía de Sola, RafaelBurgueño Torres, Laura616.314-053.2616.71615.849Osteogenesis imperfectaBasilar invaginationCranial baseCraniocervical junctionPlatybasiaCiencias BiomédicasOdontología (Medicina)Odontología infantilDiagnóstico por imagen y medicina nuclear32 Ciencias Médicas3207.14 OsteopatologíaOsteogenesis Imperfecta (OI) is a disease that causes bone fragility and deformities, affecting both the cranial base and the craniocervical junction, and may lead to other neurological disorders. A retrospective cross-sectional study was carried out based on cephalometric analysis of the cranial base in a sample of patients with OI, in lateral skull radiographs and magnetic resonance imaging (MRI), comparing them with a sample of age-matched controls. When the different variables of the craniocervical junction were analyzed, significance was found in comparisons with the different age groups. All measurements of the variables studied stabilized as growth progressed. For most of the variables, the severity of the disease influences the measurements of the skull base, with statistically significant differences. Both age and severity of the disease are factors that directly influence the anatomy of the craniocervical junction in these patients and may serve as indicators in the early detection and prevention of other derived alterations.MDPIUniversidad Complutense de Madrid20232023-06-0820232023-06-08journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/102325reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1023252026-06-02T12:44:21Z
dc.title.none.fl_str_mv Influence of the severity of osteogenesis imperfecta on cranial measurements
title Influence of the severity of osteogenesis imperfecta on cranial measurements
spellingShingle Influence of the severity of osteogenesis imperfecta on cranial measurements
Nova García, Manuel Joaquín De
616.314-053.2
616.71
615.849
Osteogenesis imperfecta
Basilar invagination
Cranial base
Craniocervical junction
Platybasia
Ciencias Biomédicas
Odontología (Medicina)
Odontología infantil
Diagnóstico por imagen y medicina nuclear
32 Ciencias Médicas
3207.14 Osteopatología
title_short Influence of the severity of osteogenesis imperfecta on cranial measurements
title_full Influence of the severity of osteogenesis imperfecta on cranial measurements
title_fullStr Influence of the severity of osteogenesis imperfecta on cranial measurements
title_full_unstemmed Influence of the severity of osteogenesis imperfecta on cranial measurements
title_sort Influence of the severity of osteogenesis imperfecta on cranial measurements
dc.creator.none.fl_str_mv Nova García, Manuel Joaquín De
García de Sola, Rafael
Burgueño Torres, Laura
author Nova García, Manuel Joaquín De
author_facet Nova García, Manuel Joaquín De
García de Sola, Rafael
Burgueño Torres, Laura
author_role author
author2 García de Sola, Rafael
Burgueño Torres, Laura
author2_role author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 616.314-053.2
616.71
615.849
Osteogenesis imperfecta
Basilar invagination
Cranial base
Craniocervical junction
Platybasia
Ciencias Biomédicas
Odontología (Medicina)
Odontología infantil
Diagnóstico por imagen y medicina nuclear
32 Ciencias Médicas
3207.14 Osteopatología
topic 616.314-053.2
616.71
615.849
Osteogenesis imperfecta
Basilar invagination
Cranial base
Craniocervical junction
Platybasia
Ciencias Biomédicas
Odontología (Medicina)
Odontología infantil
Diagnóstico por imagen y medicina nuclear
32 Ciencias Médicas
3207.14 Osteopatología
description Osteogenesis Imperfecta (OI) is a disease that causes bone fragility and deformities, affecting both the cranial base and the craniocervical junction, and may lead to other neurological disorders. A retrospective cross-sectional study was carried out based on cephalometric analysis of the cranial base in a sample of patients with OI, in lateral skull radiographs and magnetic resonance imaging (MRI), comparing them with a sample of age-matched controls. When the different variables of the craniocervical junction were analyzed, significance was found in comparisons with the different age groups. All measurements of the variables studied stabilized as growth progressed. For most of the variables, the severity of the disease influences the measurements of the skull base, with statistically significant differences. Both age and severity of the disease are factors that directly influence the anatomy of the craniocervical junction in these patients and may serve as indicators in the early detection and prevention of other derived alterations.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-06-08
2023
2023-06-08
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/102325
url https://hdl.handle.net/20.500.14352/102325
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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