Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms

This dataset corresponds to the article "Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms." It includes data on the formulation and characterization of Δ9-THC-loaded PLGA nanoparticles (NPs) prepared via nanoprecipitation. Surface modific...

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Autores: Martín Banderas, Lucía, Muñoz Rubio, Inmaculada, Álvarez Fuentes, Josefa, Durán Lobato, María Matilde, Arias, José L., Holgado Villafuerte, María Ángeles, Fernández Arévalo, María Mercedes
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/167599
Acceso en línea:https://hdl.handle.net/11441/167599
https://doi.org/10.12795/11441/167599
Access Level:acceso abierto
Palabra clave:Blood compatibility
Cannabinoids
Cellular uptake
Cytotoxicity
PLGA nanoparticles
Surface functionalization
9 -Tetrahydrocannabinol
Compatibilidad sanguínea
Cannabinoides
Captación celular
Citotoxicidad
Nanopartículas de PLGA
Funcionalización de superficie
Δ9-Tetrahidrocannabinol
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network_acronym_str ES
network_name_str España
repository_id_str
spelling Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatformsMartín Banderas, LucíaMuñoz Rubio, InmaculadaÁlvarez Fuentes, JosefaDurán Lobato, María MatildeArias, José L.Holgado Villafuerte, María ÁngelesFernández Arévalo, María MercedesBlood compatibilityCannabinoidsCellular uptakeCytotoxicityPLGA nanoparticlesSurface functionalization9 -TetrahydrocannabinolCompatibilidad sanguíneaCannabinoidesCaptación celularCitotoxicidadNanopartículas de PLGAFuncionalización de superficieΔ9-TetrahidrocannabinolThis dataset corresponds to the article "Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms." It includes data on the formulation and characterization of Δ9-THC-loaded PLGA nanoparticles (NPs) prepared via nanoprecipitation. Surface modifications include PEG, chitosan and PEG-chitosan coatings. The dataset encompasses particle size, zeta potential, encapsulation efficiency, drug loading, in vitro drug release profiles, cellular uptake (Caco-2 cells), and cytotoxicity assays.A single Excel file with each sheet collecting the data corresponding to a figure or table: -Figure 1: Data corresponding to manuscript Figure 1 on NPs physicochemical characterization. -Figure 3: Data corresponding to manuscript Figure 3 on the release profile of the different formulations at pH 2 and 7.4. -Figure 4: Data corresponding to manuscript Figure 4 on cell uptake of PLGA, PEG-PLGA and PEG-CS-PLGA NPs. -Figure 5: Data corresponding to manuscript Figure 5 on the cytotoxic effect on Caco-2 cells of free 9-THC, plain PLGA THC-loaded NPs, PEG-PLGA THC-loaded NPs, and PEG-CS-PLGA THC-loaded NPs.Farmacia y Tecnología FarmacéuticaCTS480: Investigación y Desarrollo Tecnológico en NanomedicinaJunta de AndalucíaInstituto de Salud Carlos IIIMartín Banderas, LucíaDurán Lobato, María MatildeMartín Banderas, LucíaÁlvarez Fuentes, JosefaDurán Lobato, María Matilde2025info:eu-repo/semantics/datasetDatasetDatasetapplication/vnd.ms-excelapplication/vnd.openxmlformats-officedocument.spreadsheetml.sheettext/plainhttps://hdl.handle.net/11441/167599https://doi.org/10.12795/11441/167599reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésMartín-Banderas, L., Munoz-Rubio, I., Álvarez-Fuentes, J., Durán-Lobato, M., Arias, J. L., Holgado, M. Á., & Fernández-Arévalo, M. (2014). Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms. Colloids and Surfaces B: Biointerfaces, 123, 114-122.P09-CTS-5029Project FIS 11/02571info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1675992026-06-17T12:51:07Z
dc.title.none.fl_str_mv Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
title Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
spellingShingle Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
Martín Banderas, Lucía
Blood compatibility
Cannabinoids
Cellular uptake
Cytotoxicity
PLGA nanoparticles
Surface functionalization
9 -Tetrahydrocannabinol
Compatibilidad sanguínea
Cannabinoides
Captación celular
Citotoxicidad
Nanopartículas de PLGA
Funcionalización de superficie
Δ9-Tetrahidrocannabinol
title_short Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
title_full Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
title_fullStr Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
title_full_unstemmed Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
title_sort Dataset of Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms
dc.creator.none.fl_str_mv Martín Banderas, Lucía
Muñoz Rubio, Inmaculada
Álvarez Fuentes, Josefa
Durán Lobato, María Matilde
Arias, José L.
Holgado Villafuerte, María Ángeles
Fernández Arévalo, María Mercedes
author Martín Banderas, Lucía
author_facet Martín Banderas, Lucía
Muñoz Rubio, Inmaculada
Álvarez Fuentes, Josefa
Durán Lobato, María Matilde
Arias, José L.
Holgado Villafuerte, María Ángeles
Fernández Arévalo, María Mercedes
author_role author
author2 Muñoz Rubio, Inmaculada
Álvarez Fuentes, Josefa
Durán Lobato, María Matilde
Arias, José L.
Holgado Villafuerte, María Ángeles
Fernández Arévalo, María Mercedes
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Farmacia y Tecnología Farmacéutica
CTS480: Investigación y Desarrollo Tecnológico en Nanomedicina
Junta de Andalucía
Instituto de Salud Carlos III
Martín Banderas, Lucía
Durán Lobato, María Matilde
Martín Banderas, Lucía
Álvarez Fuentes, Josefa
Durán Lobato, María Matilde
dc.subject.none.fl_str_mv Blood compatibility
Cannabinoids
Cellular uptake
Cytotoxicity
PLGA nanoparticles
Surface functionalization
9 -Tetrahydrocannabinol
Compatibilidad sanguínea
Cannabinoides
Captación celular
Citotoxicidad
Nanopartículas de PLGA
Funcionalización de superficie
Δ9-Tetrahidrocannabinol
topic Blood compatibility
Cannabinoids
Cellular uptake
Cytotoxicity
PLGA nanoparticles
Surface functionalization
9 -Tetrahydrocannabinol
Compatibilidad sanguínea
Cannabinoides
Captación celular
Citotoxicidad
Nanopartículas de PLGA
Funcionalización de superficie
Δ9-Tetrahidrocannabinol
description This dataset corresponds to the article "Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms." It includes data on the formulation and characterization of Δ9-THC-loaded PLGA nanoparticles (NPs) prepared via nanoprecipitation. Surface modifications include PEG, chitosan and PEG-chitosan coatings. The dataset encompasses particle size, zeta potential, encapsulation efficiency, drug loading, in vitro drug release profiles, cellular uptake (Caco-2 cells), and cytotoxicity assays.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
Dataset
Dataset
format dataset
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/167599
https://doi.org/10.12795/11441/167599
url https://hdl.handle.net/11441/167599
https://doi.org/10.12795/11441/167599
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Martín-Banderas, L., Munoz-Rubio, I., Álvarez-Fuentes, J., Durán-Lobato, M., Arias, J. L., Holgado, M. Á., & Fernández-Arévalo, M. (2014). Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms. Colloids and Surfaces B: Biointerfaces, 123, 114-122.
P09-CTS-5029
Project FIS 11/02571
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/vnd.ms-excel
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
text/plain
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419069282713600
score 15.81155

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