Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis

[Background & Aims] Advanced hepatic fibrosis is the main risk factor of liver-related morbidity and mortality in patients with chronic liver disease. In this study, we assessed the potential role of bone morphogenetic protein 8A (BMP8A) as a novel target involved in liver fibrosis progression.

Detalles Bibliográficos
Autores: Marañón, Patricia, Isaza, Stephania C., Fernández-García, Carlos Ernesto, Rey, Esther, Gallego-Durán, Rocío, Montero-Vallejo, Rocío, Rodríguez de Cía, Javier, Ampuero, Javier, Valverde, Ángela M., Romero-Gómez, Manuel, García-Monzón, Carmelo, González-Rodríguez, Águeda
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/333207
Acceso en línea:http://hdl.handle.net/10261/333207
https://api.elsevier.com/content/abstract/scopus_id/85156268525
Access Level:acceso abierto
Palabra clave:Non-invasive diagnosis
BMP8A
Bone morphogenetic proteins
Hepatic stellate cells
Liver fibrosis
Descripción
Sumario:[Background & Aims] Advanced hepatic fibrosis is the main risk factor of liver-related morbidity and mortality in patients with chronic liver disease. In this study, we assessed the potential role of bone morphogenetic protein 8A (BMP8A) as a novel target involved in liver fibrosis progression.