Exploring Transduction and Adaptation of Plasmids in Antimicrobial Resistance
Antimicrobial resistance (AMR) has become a growing public health threat worldwide. The increasing use and misuse of antibiotics since their introduction into the clinical setting hasled to the emergence of bacteria resistant to multiple antimicrobial agents, resulting in infections that are increas...
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| Tipo de recurso: | tesis doctoral |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | español |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/105273 |
| Acceso en línea: | https://hdl.handle.net/20.500.14352/105273 |
| Access Level: | acceso abierto |
| Palabra clave: | 579.25(043.2) Plásmidos Plasmids Microbiología (Veterinaria) 3109.05 Microbiología |
| Sumario: | Antimicrobial resistance (AMR) has become a growing public health threat worldwide. The increasing use and misuse of antibiotics since their introduction into the clinical setting hasled to the emergence of bacteria resistant to multiple antimicrobial agents, resulting in infections that are increasingly difficult to treat. Plasmids are an important vehicle for AMR genes and can serve as reservoirs and facilitate their spread. Therefore, plasmid biology is being studied thoroughly to understand the mechanisms of plasmid adaptation, transmission, and persistence to use the gained knowledge to appropriately address this issue. ColE1-likeplasmids form a widespread plasmid family that is frequently associated with the dissemination of resistance genes and has been shown to give rise to multidrug-resistant pathogens... |
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