Gamma-Carboline Synthesis by Heterocyclization of TosMIC Derivatives

A new method for the synthesis of gamma-carbolines by a heterocyclization that involves alpha-indol-2-ylmethyl TosMIC derivatives and different electrophiles has been developed. This methodology has been successfully applied to the synthesis of several highly substituted gamma-carbolines.

Detalles Bibliográficos
Autores: Gutiérrez Hernández, Sara, Sucunza Sáenz, David|||0000-0002-3307-4204, Vaquero López, Juan José|||0000-0002-3820-9673
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/43888
Acceso en línea:http://hdl.handle.net/10017/43888
https://dx.doi.org/10.1021/acs.joc.8b00906
Access Level:acceso abierto
Palabra clave:Química
Chemistry
Descripción
Sumario:A new method for the synthesis of gamma-carbolines by a heterocyclization that involves alpha-indol-2-ylmethyl TosMIC derivatives and different electrophiles has been developed. This methodology has been successfully applied to the synthesis of several highly substituted gamma-carbolines.