Domesticating predatory bacteria for biotechnological tools
As with many findings in science, the Bdellovibrio group of predatory bacteria and like organisms (Bdellovibrio and like organisms, BALOs) was discovered by serendipity (Stolp and Starr, 1963). Since they were identified, the scientific community has striven to describe their biphasic growth cycle,...
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| Formato: | tesis doctoral |
| Fecha de publicación: | 2019 |
| País: | España |
| Recursos: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/17335 |
| Acesso em linha: | https://hdl.handle.net/20.500.14352/17335 |
| Access Level: | acceso abierto |
| Palavra-chave: | 579.8(043.2) Bacterias Bacteria Bioquímica (Química) |
| Resumo: | As with many findings in science, the Bdellovibrio group of predatory bacteria and like organisms (Bdellovibrio and like organisms, BALOs) was discovered by serendipity (Stolp and Starr, 1963). Since they were identified, the scientific community has striven to describe their biphasic growth cycle, investigating and characterizing the predation mechanism. Prey selectivity and the ecological role of the predators in their natural niches have also been studied. Another crucial factor to be addressed involves an understanding of the genotypic and phenotypic changes giving rise to host-independent (HI) mutant development (Jurkevitch, 2006; Sockett, 2009a). Progress made in the last few decades in the field of predatory bacteria involves both classical molecular genetics and biochemical characterization, such as central metabolism and TCA cycle (Hespell et al., 1973). Analyses at system level have also been performed, including -omic techniques, such as transcriptomic and proteomic analyses (Barabote et al., 2007; Karunker et al., 2013)... |
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