Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis

26 páginas.- 28 figuras.- 71 referencias

Detalhes bibliográficos
Autores: Aranda, Carmen, Oksdath-Mansilla, G., Bisogno, Fabricio R., Gonzalo, Gonzalo de
Tipo de documento: artigo
Estado:Versión aceptada para publicación
Data de publicação:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/199938
Acesso em linha:http://hdl.handle.net/10261/199938
Access Level:Acceso aberto
Palavra-chave:Biocatalysis
Chiral amines
Deracemisation
Enantioselectivity
Organocatalysis
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spelling Deracemisation Processes Employing Organocatalysis and Enzyme CatalysisAranda, CarmenOksdath-Mansilla, G.Bisogno, Fabricio R.Gonzalo, Gonzalo deBiocatalysisChiral aminesDeracemisationEnantioselectivityOrganocatalysis26 páginas.- 28 figuras.- 71 referenciasDeracemisation methods have demonstrated their importance in the preparation of chiral compounds in the last few years. In order to resolve a racemic mixture in a dynamic sense, one enantiomer of the starting material can be converted to the other through a deracemisation procedure, that can be achieved by different mechanisms based on stereoinversion or enantioconvergence, often involving two‐opposite half reactions, with at least one of the reactions being enantioselective enough to finally obtain an enantioenriched chiral compound. The focus of this comprehensive review is on the application of deracemisation procedures in the present century in order to obtain optically active valuable compounds when employing non‐metallic catalysts. Thus, the review will mainly focus on the use of different enzymatic preparations (purified enzymes, cell‐free extracts or whole cell systems) and organocatalysts for the deracemisation of racemic mixtures.We thank Martin G. López-Vidal for his collaboration.G.d.G. thanks MINECO for Ramón y Cajal Program and CTQ2016-76908-C2-1,2-P projects. G.O-M. and F.R.B. ac-knowledge INFIQC-CONICET and Universidad Nacionalde Cordoba (UNC) and also thank FONCyT as well asSECyT-UNC for research funding.Peer reviewedJohn Wiley & SonsMinisterio de Economía y Competitividad (España)Universidad Nacional de Córdoba (Argentina)Fondo para la Investigación Científica y Tecnológica (Argentina)Aranda, Carmen [0000-0001-8213-1132]Oksdath-Mansilla, G. [0000-0002-8999-3314]Bisogno, Fabricio R. [0000-0002-9153-1274]Gonzalo, Gonzalo de [0000-0002-0863-680X]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202020202020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/199938reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2016-76908-C2-1-Pinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2016-76908-C2-2-Phttp://dx.doi.org/10.1002/adsc.201901112Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1999382026-05-22T06:33:51Z
dc.title.none.fl_str_mv Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
title Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
spellingShingle Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
Aranda, Carmen
Biocatalysis
Chiral amines
Deracemisation
Enantioselectivity
Organocatalysis
title_short Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
title_full Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
title_fullStr Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
title_full_unstemmed Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
title_sort Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
dc.creator.none.fl_str_mv Aranda, Carmen
Oksdath-Mansilla, G.
Bisogno, Fabricio R.
Gonzalo, Gonzalo de
author Aranda, Carmen
author_facet Aranda, Carmen
Oksdath-Mansilla, G.
Bisogno, Fabricio R.
Gonzalo, Gonzalo de
author_role author
author2 Oksdath-Mansilla, G.
Bisogno, Fabricio R.
Gonzalo, Gonzalo de
author2_role author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Universidad Nacional de Córdoba (Argentina)
Fondo para la Investigación Científica y Tecnológica (Argentina)
Aranda, Carmen [0000-0001-8213-1132]
Oksdath-Mansilla, G. [0000-0002-8999-3314]
Bisogno, Fabricio R. [0000-0002-9153-1274]
Gonzalo, Gonzalo de [0000-0002-0863-680X]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Biocatalysis
Chiral amines
Deracemisation
Enantioselectivity
Organocatalysis
topic Biocatalysis
Chiral amines
Deracemisation
Enantioselectivity
Organocatalysis
description 26 páginas.- 28 figuras.- 71 referencias
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/199938
url http://hdl.handle.net/10261/199938
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2016-76908-C2-1-P
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2016-76908-C2-2-P
http://dx.doi.org/10.1002/adsc.201901112
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,198674

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