Metal-free catalyzed ring-opening polymerization and block copolymerization of ¿-pentadecalactone using amino-ended initiators

Metal-free catalysis was successfully applied to polymerize ¿-pentadecalactone (PDL) by ring-opening polymerization (ROP) using several amino-ended initiators, namely hexylamine, allylamine and O,O'-bis(3-aminopropyl)diethylene glycol. This polymerization method was suitable to prepare telechel...

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Detalles Bibliográficos
Autores: Tinajero, Ernesto|||0000-0001-5993-8114, Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon|||0000-0001-8105-2168, Muñoz Guerra, Sebastián|||0000-0002-4273-2301, de Paz, Maria Viola, Galbis Fuster, Elsa
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/121853
Acceso en línea:https://hdl.handle.net/2117/121853
https://dx.doi.org/10.1016/j.eurpolymj.2018.09.006
Access Level:acceso abierto
Palabra clave:Nanocomposites (Materials)
Polyesters
Polymerization
Macrolactones polymerization
Amphiphilic block copolymers
Enzymatic ring-opening polymerization
Polyethyleneglycol-polyester copolymers
Amphiphilic block copolymer nanoparticles
Nanocompòsits (Materials)
Poliester
Polimerització
Àrees temàtiques de la UPC::Enginyeria química
Descripción
Sumario:Metal-free catalysis was successfully applied to polymerize ¿-pentadecalactone (PDL) by ring-opening polymerization (ROP) using several amino-ended initiators, namely hexylamine, allylamine and O,O'-bis(3-aminopropyl)diethylene glycol. This polymerization method was suitable to prepare telechelic polyesters carrying functional-end groups. The technique was then extended to the synthesis of block copolymers by ROP of PDL using bisamino-ended poly(ethylene glycol) (Mn¿=¿2600) as macroinitiator. PPDLx-PEG56-PPDLx triblock copolymers with Mn ranging between ~4000 and ~90,000¿g¿·mol-1 were synthesized and extensively characterized by NMR, DSC, TGA and XRD. The amphiphilic copolymers thus produced were demonstrated to be able to self-assemble in nanoparticles with average diameters of ~100–200¿nm and morphologies highly depending on blocks lengths. The described synthetic route distinguishes in providing “clean” amphiphilic copolymers, which are attractive candidates for biomedical applications.