Exploring Intensity-Dependent Echogenic Response to Percutaneous Electrolysis in Tendon Tissue: A Cadaveric Study
Background: Percutaneous electrolysis (PE) is an emerging therapeutic approach for tendinopathies, applying a galvanic current through a dry-needling needle to induce regenerative tissue responses. However, current dosing strategies are often empirical and lack objective physiological feedback. Obje...
| Autores: | , , , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:20.500.12328/5145 |
| Acesso em linha: | http://hdl.handle.net/20.500.12328/5145 https://doi.org/10.3390/jcm14134772 |
| Access Level: | acceso abierto |
| Palavra-chave: | Percutaneous electrolysis Dosage Quantitave ultrasound Echogenic response Galvanic current Cadaveric tendon Electrólisis percutánea Dosificación Ecografía cuantitativa Respuesta ecogénica Corriente galvánica Tendón cadavérico Electròlisi percutània Dosatge Ecografia quantitativa Resposta ecogènica Corrent galvànic Tendó cadavèric 616.7 |
| Resumo: | Background: Percutaneous electrolysis (PE) is an emerging therapeutic approach for tendinopathies, applying a galvanic current through a dry-needling needle to induce regenerative tissue responses. However, current dosing strategies are often empirical and lack objective physiological feedback. Objective: This study aimed to evaluate the echogenic effects of different galvanic current intensities on cadaveric tendon tissue using quantitative ultrasound. Methods: An ex vivo study was conducted on 29 cadaveric patellar tendon samples, each exposed to a single intensity (0–10 mA for 1 s). Quantitative ultrasound analysis was performed post-intervention, and echogenic variables were extracted using UZ eDosifier software. A composite variable, Electrolysis_UZ_Dose, was created via multiple regression to capture the overall ultrasound-visible changes. Data were analyzed using correlation, regression models, and dose–range comparisons. Results: An intensity-dependent response was observed in key echogenic parameters. Minimal changes occurred at low intensities (0–2 mA), whereas a progressive response emerged between 2 and 6 mA. Beyond 6 mA, a plateau effect suggested either tissue saturation or imaging limitations due to gasinduced acoustic shadowing. The Electrolysis_UZ_Dose variable strongly correlated with applied intensity (R2 = 0.732). Conclusions: This study suggests an intensity-dependent echogenic effect of PE on tendon tissue in key ultrasound-derived parameters (A_Number, A_Area, A_Perimeter, A_Homogeneity, and A_ASM). However, as this study was conducted under experimental conditions with a single 1 s application per sample, the results should not be extrapolated to clinical practice without further validation. |
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