Aplicació terapèutica dels compostos organometal·lics

In recent years, organometallic chemistry has acquired an important role in clinical practice, although it exists a wide variety of organic structures linked to metals in nature, and involved in biological processes. The most commonly used metals in therapy are Fe, Ag and Au even though studies with...

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Detalhes bibliográficos
Autores: López Noguera, Queralt, Dinarès Milà, M. Immaculada
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/125930
Acesso em linha:https://hdl.handle.net/2445/125930
Access Level:acceso abierto
Palavra-chave:Química organometàl·lica
Compostos organometàl·lics
Compostos heterocíclics
Carbens
Organometallic chemistry
Organometallic compounds
Heterocyclic compounds
Carbenes
Descrição
Resumo:In recent years, organometallic chemistry has acquired an important role in clinical practice, although it exists a wide variety of organic structures linked to metals in nature, and involved in biological processes. The most commonly used metals in therapy are Fe, Ag and Au even though studies with other metals, such as Ru and Rh, are increasing. The organometallic compounds have been evaluated as chemotherapeutic, antibacterial agents, radioimaging and fluorescence agents, among other applications. Ferrocene derivatives or N-heterocyclic carbenes (NHC) are structures with greater potential in these areas. This work is a review of the applications of organometallic compounds families and is highlighted the features from those that have stood out in their application field.