Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

Papandreou C; Babio N; Díaz-López A; Martínez-González MÁ; Becerra-Tomas N; Corella D; Schröder H; Romaguera D; Alonso-Gómez ÁM; Wärnberg J; Martínez AJ; Serra-Majem L; Estruch R; Muñoz-Garach A; Lapetra J; Pintó X; Tur JA; Garcia-Rios A; Bueno-Cavanillas A; Delgado-Rodríguez M; Matía-Martín P; Daimiel L; M Sánchez V; Vidal J; Vázquez C; Ros E; Ruiz-Canela M; Bulló M; Sorli JV; Quifer M; Colom A; Oncina-Canovas A; T Sierra L; Barón-López J; Pérez-Farinós N; Abete I; Sanchez-Villegas A; Casas R; F García JC; Santos-Lozano JM; Corbella E; Del M Bibiloni M; Diez-Espino J; Asensio EM; Torras L; Morey M; Compañ-Gabucio L; S Lete I; Cenoz-Osinaga JC; Castañer O; Salas-Salvadó J

Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndrome in the (Prevenc...

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Authors:	Papandreou C, Babio N, Díaz-López A, Martínez-González MÁ, Becerra-Tomas N, Corella D, Schröder H, Romaguera D, Alonso-Gómez ÁM, Wärnberg J, Martínez AJ, Serra-Majem L, Estruch R, Muñoz-Garach A, Lapetra J, Pintó X, Tur JA, Garcia-Rios A, Bueno-Cavanillas A, Delgado-Rodríguez M, Matía-Martín P, Daimiel L, M Sánchez V, Vidal J, Vázquez C, Ros E, Ruiz-Canela M, Bulló M, Sorli JV, Quifer M, Colom A, Oncina-Canovas A, T Sierra L, Barón-López J, Pérez-Farinós N, Abete I, Sanchez-Villegas A, Casas R, F García JC, Santos-Lozano JM, Corbella E, Del M Bibiloni M, Diez-Espino J, Asensio EM, Torras L, Morey M, Compañ-Gabucio L, S Lete I, Cenoz-Osinaga JC, Castañer O, Salas-Salvadó J
Format:	article
Status:	Published version
Publication Date:	2019
Country:	España
Institution:	Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repository:	r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:	oai:fisabio.fundanetsuite.com:p4501
Online Access:	https://fisabio.portalinvestigacion.com/publicaciones/4501
Access Level:	Open access
Keyword:	sleep duration actigraphy serum uric acid serum uric acid to creatinine ratio

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spelling	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular RiskPapandreou CBabio NDíaz-López AMartínez-González MÁBecerra-Tomas NCorella DSchröder HRomaguera DAlonso-Gómez ÁMWärnberg JMartínez AJSerra-Majem LEstruch RMuñoz-Garach ALapetra JPintó XTur JAGarcia-Rios ABueno-Cavanillas ADelgado-Rodríguez MMatía-Martín PDaimiel LM Sánchez VVidal JVázquez CRos ERuiz-Canela MBulló MSorli JVQuifer MColom AOncina-Canovas AT Sierra LBarón-López JPérez-Farinós NAbete ISanchez-Villegas ACasas RF García JCSantos-Lozano JMCorbella EDel M Bibiloni MDiez-Espino JAsensio EMTorras LMorey MCompañ-Gabucio LS Lete ICenoz-Osinaga JCCastañer OSalas-Salvadó Jsleep durationactigraphyserum uric acidserum uric acid to creatinine ratioThe aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndrome in the (Prevencion con Dieta Mediterranea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations ( = -0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio ( = -0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.MDPI2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/4501NutrientsISSN: 20726643reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p45012026-06-11T12:45:17Z
dc.title.none.fl_str_mv	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
title	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
spellingShingle	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk Papandreou C sleep duration actigraphy serum uric acid serum uric acid to creatinine ratio
title_short	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
title_full	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
title_fullStr	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
title_full_unstemmed	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
title_sort	Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
dc.creator.none.fl_str_mv	Papandreou C Babio N Díaz-López A Martínez-González MÁ Becerra-Tomas N Corella D Schröder H Romaguera D Alonso-Gómez ÁM Wärnberg J Martínez AJ Serra-Majem L Estruch R Muñoz-Garach A Lapetra J Pintó X Tur JA Garcia-Rios A Bueno-Cavanillas A Delgado-Rodríguez M Matía-Martín P Daimiel L M Sánchez V Vidal J Vázquez C Ros E Ruiz-Canela M Bulló M Sorli JV Quifer M Colom A Oncina-Canovas A T Sierra L Barón-López J Pérez-Farinós N Abete I Sanchez-Villegas A Casas R F García JC Santos-Lozano JM Corbella E Del M Bibiloni M Diez-Espino J Asensio EM Torras L Morey M Compañ-Gabucio L S Lete I Cenoz-Osinaga JC Castañer O Salas-Salvadó J
author	Papandreou C
author_facet	Papandreou C Babio N Díaz-López A Martínez-González MÁ Becerra-Tomas N Corella D Schröder H Romaguera D Alonso-Gómez ÁM Wärnberg J Martínez AJ Serra-Majem L Estruch R Muñoz-Garach A Lapetra J Pintó X Tur JA Garcia-Rios A Bueno-Cavanillas A Delgado-Rodríguez M Matía-Martín P Daimiel L M Sánchez V Vidal J Vázquez C Ros E Ruiz-Canela M Bulló M Sorli JV Quifer M Colom A Oncina-Canovas A T Sierra L Barón-López J Pérez-Farinós N Abete I Sanchez-Villegas A Casas R F García JC Santos-Lozano JM Corbella E Del M Bibiloni M Diez-Espino J Asensio EM Torras L Morey M Compañ-Gabucio L S Lete I Cenoz-Osinaga JC Castañer O Salas-Salvadó J
author_role	author
author2	Babio N Díaz-López A Martínez-González MÁ Becerra-Tomas N Corella D Schröder H Romaguera D Alonso-Gómez ÁM Wärnberg J Martínez AJ Serra-Majem L Estruch R Muñoz-Garach A Lapetra J Pintó X Tur JA Garcia-Rios A Bueno-Cavanillas A Delgado-Rodríguez M Matía-Martín P Daimiel L M Sánchez V Vidal J Vázquez C Ros E Ruiz-Canela M Bulló M Sorli JV Quifer M Colom A Oncina-Canovas A T Sierra L Barón-López J Pérez-Farinós N Abete I Sanchez-Villegas A Casas R F García JC Santos-Lozano JM Corbella E Del M Bibiloni M Diez-Espino J Asensio EM Torras L Morey M Compañ-Gabucio L S Lete I Cenoz-Osinaga JC Castañer O Salas-Salvadó J
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	sleep duration actigraphy serum uric acid serum uric acid to creatinine ratio
topic	sleep duration actigraphy serum uric acid serum uric acid to creatinine ratio
description	The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndrome in the (Prevencion con Dieta Mediterranea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations ( = -0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio ( = -0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
publishDate	2019
dc.date.none.fl_str_mv	2019
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://fisabio.portalinvestigacion.com/publicaciones/4501
url	https://fisabio.portalinvestigacion.com/publicaciones/4501
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	MDPI
publisher.none.fl_str_mv	MDPI
dc.source.none.fl_str_mv	Nutrients ISSN: 20726643 reponame:r-FISABIO. Repositorio Institucional de Producción Científica instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str	Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str	r-FISABIO. Repositorio Institucional de Producción Científica
collection	r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869418123812143104
score	15,812429

Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

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