Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-Catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes

The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction provides good yields of optically active cyclohexenes featuring diverse substitution patterns and up to three stereocenters. Key to the success of the process is the use of new...

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Detalles Bibliográficos
Autores: Francos Arias, Javier, Grande-Carmona, Francisca, Faustino, Hélio, Iglesias Sigüenza, Francisco Javier, Díez Martín, Elena, Alonso García, Isaac, Fernández Fernández, Rosario Fátima, Lassaletta, José M., López García, Fernando, Mascareñas Cid, José Luis
Tipo de recurso: artículo
Fecha de publicación:2012
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/18480
Acceso en línea:http://hdl.handle.net/10347/18480
Access Level:acceso abierto
Descripción
Sumario:The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction provides good yields of optically active cyclohexenes featuring diverse substitution patterns and up to three stereocenters. Key to the success of the process is the use of newly designed axially chiral N-heterocyclic carbene–gold catalysts

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