Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse. Therefore, this study aimed to analyse how...

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Detalles Bibliográficos
Autores: Herrainz, Adela, Álvarez-García, Jesus, Llach, A, Molina, Cristina E., Fernandes, Jacqueline, Ferrero-Gregori, Andreu, Rodríguez, Cristina, Vallmitjana Lees, Alexander, Benítez Iglesias, Raúl|||0000-0002-8782-9406, Padró, Josep M., Martínez-González, José, Cinca Cosculluela, Juan, Hove-Madsen, Leif|||0000-0001-5493-3998
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/76191
Acceso en línea:https://hdl.handle.net/2117/76191
https://dx.doi.org/10.1093/cvr/cvv046
Access Level:acceso abierto
Palabra clave:Biomedical engineering
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
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repository_id_str
spelling Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytesHerrainz, AdelaÁlvarez-García, JesusLlach, AMolina, Cristina E.Fernandes, JacquelineFerrero-Gregori, AndreuRodríguez, CristinaVallmitjana Lees, AlexanderBenítez Iglesias, Raúl|||0000-0002-8782-9406Padró, Josep M.Martínez-González, JoséCinca Cosculluela, JuanHove-Madsen, Leif|||0000-0001-5493-3998Biomedical engineeringEnginyeria biomèdicaÀrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdicaAgeing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse. Therefore, this study aimed to analyse how ageing affects key mechanisms that regulate intracellular calcium in human atrial myocytes.Peer Reviewed20152015-02-2420152015-07-17journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/76191https://dx.doi.org/10.1093/cvr/cvv04625712961reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)InglésengEuropean Commission http://dx.doi.org/10.13039/100011102 Seventh Framework Programme 331241 Effects of atrial fibrillation on the distribution and frequency of spontaneous calcium release events in human atrial myocytesopen accesshttp://purl.org/coar/access_right/c_abf2http://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/761912026-05-27T15:37:01Z
dc.title.none.fl_str_mv Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
title Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
spellingShingle Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
Herrainz, Adela
Biomedical engineering
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
title_short Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
title_full Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
title_fullStr Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
title_full_unstemmed Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
title_sort Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
dc.creator.none.fl_str_mv Herrainz, Adela
Álvarez-García, Jesus
Llach, A
Molina, Cristina E.
Fernandes, Jacqueline
Ferrero-Gregori, Andreu
Rodríguez, Cristina
Vallmitjana Lees, Alexander
Benítez Iglesias, Raúl|||0000-0002-8782-9406
Padró, Josep M.
Martínez-González, José
Cinca Cosculluela, Juan
Hove-Madsen, Leif|||0000-0001-5493-3998
author Herrainz, Adela
author_facet Herrainz, Adela
Álvarez-García, Jesus
Llach, A
Molina, Cristina E.
Fernandes, Jacqueline
Ferrero-Gregori, Andreu
Rodríguez, Cristina
Vallmitjana Lees, Alexander
Benítez Iglesias, Raúl|||0000-0002-8782-9406
Padró, Josep M.
Martínez-González, José
Cinca Cosculluela, Juan
Hove-Madsen, Leif|||0000-0001-5493-3998
author_role author
author2 Álvarez-García, Jesus
Llach, A
Molina, Cristina E.
Fernandes, Jacqueline
Ferrero-Gregori, Andreu
Rodríguez, Cristina
Vallmitjana Lees, Alexander
Benítez Iglesias, Raúl|||0000-0002-8782-9406
Padró, Josep M.
Martínez-González, José
Cinca Cosculluela, Juan
Hove-Madsen, Leif|||0000-0001-5493-3998
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Biomedical engineering
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
topic Biomedical engineering
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
description Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse. Therefore, this study aimed to analyse how ageing affects key mechanisms that regulate intracellular calcium in human atrial myocytes.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-02-24
2015
2015-07-17
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/76191
https://dx.doi.org/10.1093/cvr/cvv046
25712961
url https://hdl.handle.net/2117/76191
https://dx.doi.org/10.1093/cvr/cvv046
identifier_str_mv 25712961
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv European Commission http://dx.doi.org/10.13039/100011102 Seventh Framework Programme 331241 Effects of atrial fibrillation on the distribution and frequency of spontaneous calcium release events in human atrial myocytes
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2

http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2

http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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