Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse. Therefore, this study aimed to analyse how...

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Detalles Bibliográficos
Autores: Herrainz, Adela, Álvarez-García, Jesus, Llach, A, Molina, Cristina E., Fernandes, Jacqueline, Ferrero-Gregori, Andreu, Rodríguez, Cristina, Vallmitjana Lees, Alexander, Benítez Iglesias, Raúl|||0000-0002-8782-9406, Padró, Josep M., Martínez-González, José, Cinca Cosculluela, Juan, Hove-Madsen, Leif|||0000-0001-5493-3998
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/76191
Acceso en línea:https://hdl.handle.net/2117/76191
https://dx.doi.org/10.1093/cvr/cvv046
Access Level:acceso abierto
Palabra clave:Biomedical engineering
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
Descripción
Sumario:Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse. Therefore, this study aimed to analyse how ageing affects key mechanisms that regulate intracellular calcium in human atrial myocytes.

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