Ultraviolet resonance Raman spectroscopy for the detection of cocaine in oral fluid
Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Rama...
| Autores: | , , , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Recursos: | Universidad de Alcalá (UAH) |
| Repositorio: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglés |
| OAI Identifier: | oai:ebuah.uah.es:10017/47418 |
| Acesso em linha: | http://hdl.handle.net/10017/47418 https://dx.doi.org/10.1016/j.saa.2017.07.010 |
| Access Level: | acceso abierto |
| Palavra-chave: | Raman spectroscopy Ultraviolet Raman spectroscopy Cocaine Oral fluid Forensic Química Chemistry |
| Resumo: | Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Raman spectroscopy to detect cocaine in oral fluid without pretreating samples was tested. It was found that ultraviolet resonance Raman spectroscopy with 239-nm excitation allows for the detection of cocaine in oral fluid at 10 mu g/mL level. Further method development will be needed for reaching the practically useful levels of cocaine detection. (C) 2017 Elsevier B.V. All rights reserved. |
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