Ultraviolet resonance Raman spectroscopy for the detection of cocaine in oral fluid

Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Rama...

Descripción completa

Detalles Bibliográficos
Autores: D'Elia, Valentina|||0000-0001-6782-5486, Montalvo García, Gemma|||0000-0002-5640-8908, García Ruiz, Carmen|||0000-0001-5925-3449, Ermolenkov, Vladimir V., Ahmed, Yasmine, Lednev, Igor K.
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/47418
Acceso en línea:http://hdl.handle.net/10017/47418
https://dx.doi.org/10.1016/j.saa.2017.07.010
Access Level:acceso abierto
Palabra clave:Raman spectroscopy
Ultraviolet Raman spectroscopy
Cocaine
Oral fluid
Forensic
Química
Chemistry
Descripción
Sumario:Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Raman spectroscopy to detect cocaine in oral fluid without pretreating samples was tested. It was found that ultraviolet resonance Raman spectroscopy with 239-nm excitation allows for the detection of cocaine in oral fluid at 10 mu g/mL level. Further method development will be needed for reaching the practically useful levels of cocaine detection. (C) 2017 Elsevier B.V. All rights reserved.