Decreased HOMA-IR levels after physical exercise as a therapy to reduce insulin resistance: A systematic review

A sedentary lifestyle can increase metabolic diseases such as diabetes mellitus. The aim of this study was to determine how physical activity reduces insulin resistance by reducing HOMA-IR levels. This study also provides a theoretical basis for physical exercise in preventing insulin resistance in...

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Detalles Bibliográficos
Autores: Wibawa, Junian Cahyanto, Putro, Baskoro Nugroho, Putra, Dany Pramuno
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad de Murcia
Repositorio:DIGITUM. Depósito Digital Institucional de la Universidad de Murcia
OAI Identifier:oai:digitum.um.es:10201/209382
Acceso en línea:https://doi.org/10.6018/sportk.652591
http://hdl.handle.net/10201/209382
Access Level:acceso abierto
Palabra clave:hysical Exercise
Physical Fitness
HOMA-IR
nsulin Resistance
No relacionado con ningún objetivo de desarrollo sostenible
Descripción
Sumario:A sedentary lifestyle can increase metabolic diseases such as diabetes mellitus. The aim of this study was to determine how physical activity reduces insulin resistance by reducing HOMA-IR levels. This study also provides a theoretical basis for physical exercise in preventing insulin resistance in humans. For our systematic review, we searched several literature databases (PubMed, Web of Science, and ScienceDirect) for articles published in the past five years that examined physical activity and HOMA-IR. A total of 422 published papers were located using the Web of Science, Pubmed, and Science Direct databases. Ten papers that satisfied the inclusion criteria were chosen and examined for this systematic review. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were used in this study to assess standard operating procedures. It has been demonstrated that regular exercise lowers insulin resistance by lowering HOMA-IR values. It has been proven that physical exercise is the best therapy for people with metabolic diseases, especially insulin resistance. Physical exercise has been shown to significantly reduce insulin resistance by decreasing HOMA-IR levels. Therefore, regular physical exercise is highly recommended as the best therapy for insulin resistance in humans.