Kernel conditional Embeddings for associating omic data types

Computational methods are needed to combine diverse type of genome-wide data in a meaningful manner. Based on the kernel embedding of conditional probability distributions, a new measure for inferring the degree of association between two multivariate data sources is introduced. We analyze the perfo...

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Bibliographic Details
Authors: Reverter Comes, Ferran, Vegas Lozano, Esteban, Oller i Sala, Josep Maria
Format: article
Status:Versión aceptada para publicación
Publication Date:2018
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/156044
Online Access:https://hdl.handle.net/2445/156044
Access Level:Open access
Keyword:Bioinformàtica
Genòmica
Bioinformatics
Genomics
Description
Summary:Computational methods are needed to combine diverse type of genome-wide data in a meaningful manner. Based on the kernel embedding of conditional probability distributions, a new measure for inferring the degree of association between two multivariate data sources is introduced. We analyze the performance of the proposed measure to integrate mRNA expression, DNA methylation and miRNA expression data.