Kernel conditional Embeddings for associating omic data types

Computational methods are needed to combine diverse type of genome-wide data in a meaningful manner. Based on the kernel embedding of conditional probability distributions, a new measure for inferring the degree of association between two multivariate data sources is introduced. We analyze the perfo...

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Detalles Bibliográficos
Autores: Reverter Comes, Ferran, Vegas Lozano, Esteban, Oller i Sala, Josep Maria
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/156044
Acceso en línea:https://hdl.handle.net/2445/156044
Access Level:acceso abierto
Palabra clave:Bioinformàtica
Genòmica
Bioinformatics
Genomics
Descripción
Sumario:Computational methods are needed to combine diverse type of genome-wide data in a meaningful manner. Based on the kernel embedding of conditional probability distributions, a new measure for inferring the degree of association between two multivariate data sources is introduced. We analyze the performance of the proposed measure to integrate mRNA expression, DNA methylation and miRNA expression data.