Cross- Coupling in flow using supported catalysts: Mild and clean Suzuki-Miyaura coupling in a single pass
A mild, clean, practical, sustainable and high yielding procedure for Suzuki–Miyaura crosscoupling in a single pass using a silica-supported palladium catalyst is described. The catalyst can be used in more than 30 reactions and for more than 8 h of continuous processing without a decrease in reacti...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2012 |
| País: | España |
| Institución: | Universidad de Castilla-La Mancha |
| Repositorio: | RUIdeRA. Repositorio Institucional de la UCLM |
| OAI Identifier: | oai:ruidera.uclm.es:10578/38740 |
| Acceso en línea: | https://hdl.handle.net/10578/38740 |
| Access Level: | acceso abierto |
| Palabra clave: | C-C bond formation cross-coupling flow chemistry solid-supported catalyst Suzuki– Miyaura reaction |
| Sumario: | A mild, clean, practical, sustainable and high yielding procedure for Suzuki–Miyaura crosscoupling in a single pass using a silica-supported palladium catalyst is described. The catalyst can be used in more than 30 reactions and for more than 8 h of continuous processing without a decrease in reactivity due to the low leaching observed. Different halides/pseudo-halides and organoboron compounds can be used without modifying the standard procedure. |
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