Electrostatic long-range stereocontrol in asymmetric Suzuki-Miyaura cross-coupling
In this issue of Chem Catalysis, Zhu and co-workers report on the development of asymmetric Suzuki-Miyaura cross-coupling using ligand-substrate electrostatic attractive interactions as the key strategy of stereocontrol. Using a sterically unbiased meta-carboxylate-substituted RuPhos derivative as t...
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| Tipo de recurso: | artículo |
| Estado: | Versión enviada para evaluación y publicación |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/354753 |
| Acceso en línea: | http://hdl.handle.net/10261/354753 https://api.elsevier.com/content/abstract/scopus_id/85150337518 |
| Access Level: | acceso abierto |
| Palabra clave: | Electrostatic Suzuki-Miyaura long-range stereocontrol asymmetric |
| Sumario: | In this issue of Chem Catalysis, Zhu and co-workers report on the development of asymmetric Suzuki-Miyaura cross-coupling using ligand-substrate electrostatic attractive interactions as the key strategy of stereocontrol. Using a sterically unbiased meta-carboxylate-substituted RuPhos derivative as the ligand, they achieved high enantioselectivities not only in the coupling of substrates decorated with acidic, deprotonable functionalities at ortho-positions but also for meta-substituted analogs. |
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