The stochastic SEIR model before extinction: computational approaches

We study a stochastic epidemic model of Susceptible-Exposed-Infective-Removed (SEIR) type and we quantify its behavior during an outbreak. More specifically, we model the epidemic by a continuous-time Markov chain and we develop efficient computational procedures for the distribution of the duration...

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Detalles Bibliográficos
Autores: Artalejo Rodríguez, Jesús Manuel, Economou, A., López Herrero, María Jesús
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/101973
Acceso en línea:https://hdl.handle.net/20.500.14352/101973
Access Level:acceso abierto
Palabra clave:519.22-76
616-036.22
519.217
519.216
Stochastic SEIR epidemic model
Extinction time
Ratio-of-expectations distribution
Procesos estocásticos
Enfermedades infecciosas
3212 Salud Publica
2404.01 Bioestadística
1208.06 Procesos de Markov
3202 Epidemiología
Descripción
Sumario:We study a stochastic epidemic model of Susceptible-Exposed-Infective-Removed (SEIR) type and we quantify its behavior during an outbreak. More specifically, we model the epidemic by a continuous-time Markov chain and we develop efficient computational procedures for the distribution of the duration of an outbreak. We also study the evolution of the epidemic before its extinction using the ratio-of-expectations (RE) distribution for the number of individuals in the various classes of the model. The obtained results are illustrated by numerical examples including an application to an outbreak of Marburg hemorrhagic fever