IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper
Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, c...
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:227656 |
| Acceso en línea: | https://ddd.uab.cat/record/227656 https://dx.doi.org/urn:doi:10.1016/j.waojou.2019.100080 |
| Access Level: | acceso abierto |
| Palabra clave: | IgE Allergy In vitro tests Skin tests Diagnostic strategies AAAAI, American Academy of Allergy Asthma and Immunology ABA, Allergen Bead Array ACAAI, American College of Allergy Asthma and Immunology AIT, allergen immunotherapy AEC, Allergen Exposure Chambers Anti-IgE, Antibody against IgE AP, Alkaline Phosphatase AU/mL, Allergenic Units milliLiter BAT, Basophil Activation Test BAU/mL, Biologic Allergenic Units milliLiter CaFE, Calibrated Fluorescence Enhancement CBA, Cytometric Bead Array CCD, Cross-reactive Carbohydrate Determinants CDER, Center for Drug Evaluation and Research (USA) CL, Chemiluminescence DBPCFC, Double-Blind Placebo-Controlled Food Challenge EAACI, European Academy of Allergy and Immunology EIA, Enzyme Immune Assay ELISA, Enzyme Linked Immuno Sorbent Analysis EMEA, European MEdicine Agencies ENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3 FACS, Fluorescence-Activated Cell Sorting FDA, Food and Drug Administration (U.S. Department of Health and Human Services) FEIA, Fluorescent Enzyme Immunoassays FcεRI, High affinity IgE receptor H1, Histamine 1 receptor H2, Histamine 2 receptor HPO, Horseradish Peroxidase IDT, Intradermal Test IgE, immunoglobulin E ISAC, Immuno-Solid phase Allergen Chip IUIS, International Union of Immunological Societies IVD, in vitro diagnostic tool Ku/l, kilo Units of Allergen/Liter for allergen-specific IgE antibody assays LAMP-3, Lysosomal-Associated Membrane Protein Mab, Monoclonal Antibody MRGPRX2, Mas-related G protein receptor 2 MBAD, Molecule Based Allergy Diagnostics NIH, National Institutes of Health (USA) NMBAs, NeuroMuscular Blocking Agents NPA, Negative Percent Agreement NSAIDs, Non-Steroidal Anti-Inflammatory Drugs Pnpp, p -Nitrophenylphosphate PPA, Positive Percent Agreement PPT, Prick-Prick Test Sige, specific IgE RAST, Radio Allergo Sorbent Test SCAR, severe cutaneous adverse drug reactions SPT, Skin prick test W/v, weight /volume |
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IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| spellingShingle |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper Ansotegui Zubeldia, Ignacio Javier|||0000-0002-6942-1511 IgE Allergy In vitro tests Skin tests Diagnostic strategies AAAAI, American Academy of Allergy Asthma and Immunology ABA, Allergen Bead Array ACAAI, American College of Allergy Asthma and Immunology AIT, allergen immunotherapy AEC, Allergen Exposure Chambers Anti-IgE, Antibody against IgE AP, Alkaline Phosphatase AU/mL, Allergenic Units milliLiter BAT, Basophil Activation Test BAU/mL, Biologic Allergenic Units milliLiter CaFE, Calibrated Fluorescence Enhancement CBA, Cytometric Bead Array CCD, Cross-reactive Carbohydrate Determinants CDER, Center for Drug Evaluation and Research (USA) CL, Chemiluminescence DBPCFC, Double-Blind Placebo-Controlled Food Challenge EAACI, European Academy of Allergy and Immunology EIA, Enzyme Immune Assay ELISA, Enzyme Linked Immuno Sorbent Analysis EMEA, European MEdicine Agencies ENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3 FACS, Fluorescence-Activated Cell Sorting FDA, Food and Drug Administration (U.S. Department of Health and Human Services) FEIA, Fluorescent Enzyme Immunoassays FcεRI, High affinity IgE receptor H1, Histamine 1 receptor H2, Histamine 2 receptor HPO, Horseradish Peroxidase IDT, Intradermal Test IgE, immunoglobulin E ISAC, Immuno-Solid phase Allergen Chip IUIS, International Union of Immunological Societies IVD, in vitro diagnostic tool Ku/l, kilo Units of Allergen/Liter for allergen-specific IgE antibody assays LAMP-3, Lysosomal-Associated Membrane Protein Mab, Monoclonal Antibody MRGPRX2, Mas-related G protein receptor 2 MBAD, Molecule Based Allergy Diagnostics NIH, National Institutes of Health (USA) NMBAs, NeuroMuscular Blocking Agents NPA, Negative Percent Agreement NSAIDs, Non-Steroidal Anti-Inflammatory Drugs Pnpp, p -Nitrophenylphosphate PPA, Positive Percent Agreement PPT, Prick-Prick Test Sige, specific IgE RAST, Radio Allergo Sorbent Test SCAR, severe cutaneous adverse drug reactions SPT, Skin prick test W/v, weight /volume |
| title_short |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_full |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_fullStr |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_full_unstemmed |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| title_sort |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper |
| dc.creator.none.fl_str_mv |
Ansotegui Zubeldia, Ignacio Javier|||0000-0002-6942-1511 Melioli, Giovanni Canonica, G. Walter|||0000-0001-8467-2557 Caraballo, Luis Villa, Elisa Ebisawa, Motohiro|||0000-0003-4117-558X Passalacqua, Giovanni|||0000-0002-5139-3604 Savi, Eleonora Ebo, Didier|||0000-0003-0672-7529 Gómez, R. Maximiliano Luengo Sánchez, Olga|||0000-0002-8905-2776 Oppenheimer, John J. Jensen-Jarolim, Erika Fischer, David A. Haahtela, Tari|||0000-0003-4757-2156 Antila, Martti Bousquet, Jean|||0000-0002-4061-4766 Cardona, Victoria|||0000-0003-2197-9767 Chiang, Wen Chin Demoly, Pascal|||0000-0001-7827-7964 DuBuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez-Estrada, Alexei Jares, E. J.|||0000-0001-9411-0582 Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mário Pfaar, Oliver|||0000-0003-4374-9639 Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosário Filho, Nelson A. Rosenwasser, Lanny Sánchez Borges, Mario|||0000-0002-9308-6418 Scala, Enrico|||0000-0002-9391-9168 Senna, Gian-Enrico Sisul, Juan Carlos Tang, Mimi L. K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten|||0000-0002-1466-8875 |
| author |
Ansotegui Zubeldia, Ignacio Javier|||0000-0002-6942-1511 |
| author_facet |
Ansotegui Zubeldia, Ignacio Javier|||0000-0002-6942-1511 Melioli, Giovanni Canonica, G. Walter|||0000-0001-8467-2557 Caraballo, Luis Villa, Elisa Ebisawa, Motohiro|||0000-0003-4117-558X Passalacqua, Giovanni|||0000-0002-5139-3604 Savi, Eleonora Ebo, Didier|||0000-0003-0672-7529 Gómez, R. Maximiliano Luengo Sánchez, Olga|||0000-0002-8905-2776 Oppenheimer, John J. Jensen-Jarolim, Erika Fischer, David A. Haahtela, Tari|||0000-0003-4757-2156 Antila, Martti Bousquet, Jean|||0000-0002-4061-4766 Cardona, Victoria|||0000-0003-2197-9767 Chiang, Wen Chin Demoly, Pascal|||0000-0001-7827-7964 DuBuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez-Estrada, Alexei Jares, E. J.|||0000-0001-9411-0582 Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mário Pfaar, Oliver|||0000-0003-4374-9639 Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosário Filho, Nelson A. Rosenwasser, Lanny Sánchez Borges, Mario|||0000-0002-9308-6418 Scala, Enrico|||0000-0002-9391-9168 Senna, Gian-Enrico Sisul, Juan Carlos Tang, Mimi L. K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten|||0000-0002-1466-8875 |
| author_role |
author |
| author2 |
Melioli, Giovanni Canonica, G. Walter|||0000-0001-8467-2557 Caraballo, Luis Villa, Elisa Ebisawa, Motohiro|||0000-0003-4117-558X Passalacqua, Giovanni|||0000-0002-5139-3604 Savi, Eleonora Ebo, Didier|||0000-0003-0672-7529 Gómez, R. Maximiliano Luengo Sánchez, Olga|||0000-0002-8905-2776 Oppenheimer, John J. Jensen-Jarolim, Erika Fischer, David A. Haahtela, Tari|||0000-0003-4757-2156 Antila, Martti Bousquet, Jean|||0000-0002-4061-4766 Cardona, Victoria|||0000-0003-2197-9767 Chiang, Wen Chin Demoly, Pascal|||0000-0001-7827-7964 DuBuske, Lawrence M. Ferrer Puga, Marta Gerth van Wijk, Roy González Díaz, Sandra Nora Gonzalez-Estrada, Alexei Jares, E. J.|||0000-0001-9411-0582 Kalpaklioğlu, Ayse Füsun Kase Tanno, Luciana Kowalski, Marek L. Ledford, Dennis K. Monge Ortega, Olga Patricia Morais Almeida, Mário Pfaar, Oliver|||0000-0003-4374-9639 Poulsen, Lars K. Pawankar, Ruby Renz, Harald E. Romano, Antonino G. Rosário Filho, Nelson A. Rosenwasser, Lanny Sánchez Borges, Mario|||0000-0002-9308-6418 Scala, Enrico|||0000-0002-9391-9168 Senna, Gian-Enrico Sisul, Juan Carlos Tang, Mimi L. K. Thong, Bernard Yu-Hor Valenta, Rudolf Wood, Robert A. Zuberbier, Torsten|||0000-0002-1466-8875 |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
IgE Allergy In vitro tests Skin tests Diagnostic strategies AAAAI, American Academy of Allergy Asthma and Immunology ABA, Allergen Bead Array ACAAI, American College of Allergy Asthma and Immunology AIT, allergen immunotherapy AEC, Allergen Exposure Chambers Anti-IgE, Antibody against IgE AP, Alkaline Phosphatase AU/mL, Allergenic Units milliLiter BAT, Basophil Activation Test BAU/mL, Biologic Allergenic Units milliLiter CaFE, Calibrated Fluorescence Enhancement CBA, Cytometric Bead Array CCD, Cross-reactive Carbohydrate Determinants CDER, Center for Drug Evaluation and Research (USA) CL, Chemiluminescence DBPCFC, Double-Blind Placebo-Controlled Food Challenge EAACI, European Academy of Allergy and Immunology EIA, Enzyme Immune Assay ELISA, Enzyme Linked Immuno Sorbent Analysis EMEA, European MEdicine Agencies ENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3 FACS, Fluorescence-Activated Cell Sorting FDA, Food and Drug Administration (U.S. Department of Health and Human Services) FEIA, Fluorescent Enzyme Immunoassays FcεRI, High affinity IgE receptor H1, Histamine 1 receptor H2, Histamine 2 receptor HPO, Horseradish Peroxidase IDT, Intradermal Test IgE, immunoglobulin E ISAC, Immuno-Solid phase Allergen Chip IUIS, International Union of Immunological Societies IVD, in vitro diagnostic tool Ku/l, kilo Units of Allergen/Liter for allergen-specific IgE antibody assays LAMP-3, Lysosomal-Associated Membrane Protein Mab, Monoclonal Antibody MRGPRX2, Mas-related G protein receptor 2 MBAD, Molecule Based Allergy Diagnostics NIH, National Institutes of Health (USA) NMBAs, NeuroMuscular Blocking Agents NPA, Negative Percent Agreement NSAIDs, Non-Steroidal Anti-Inflammatory Drugs Pnpp, p -Nitrophenylphosphate PPA, Positive Percent Agreement PPT, Prick-Prick Test Sige, specific IgE RAST, Radio Allergo Sorbent Test SCAR, severe cutaneous adverse drug reactions SPT, Skin prick test W/v, weight /volume |
| topic |
IgE Allergy In vitro tests Skin tests Diagnostic strategies AAAAI, American Academy of Allergy Asthma and Immunology ABA, Allergen Bead Array ACAAI, American College of Allergy Asthma and Immunology AIT, allergen immunotherapy AEC, Allergen Exposure Chambers Anti-IgE, Antibody against IgE AP, Alkaline Phosphatase AU/mL, Allergenic Units milliLiter BAT, Basophil Activation Test BAU/mL, Biologic Allergenic Units milliLiter CaFE, Calibrated Fluorescence Enhancement CBA, Cytometric Bead Array CCD, Cross-reactive Carbohydrate Determinants CDER, Center for Drug Evaluation and Research (USA) CL, Chemiluminescence DBPCFC, Double-Blind Placebo-Controlled Food Challenge EAACI, European Academy of Allergy and Immunology EIA, Enzyme Immune Assay ELISA, Enzyme Linked Immuno Sorbent Analysis EMEA, European MEdicine Agencies ENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3 FACS, Fluorescence-Activated Cell Sorting FDA, Food and Drug Administration (U.S. Department of Health and Human Services) FEIA, Fluorescent Enzyme Immunoassays FcεRI, High affinity IgE receptor H1, Histamine 1 receptor H2, Histamine 2 receptor HPO, Horseradish Peroxidase IDT, Intradermal Test IgE, immunoglobulin E ISAC, Immuno-Solid phase Allergen Chip IUIS, International Union of Immunological Societies IVD, in vitro diagnostic tool Ku/l, kilo Units of Allergen/Liter for allergen-specific IgE antibody assays LAMP-3, Lysosomal-Associated Membrane Protein Mab, Monoclonal Antibody MRGPRX2, Mas-related G protein receptor 2 MBAD, Molecule Based Allergy Diagnostics NIH, National Institutes of Health (USA) NMBAs, NeuroMuscular Blocking Agents NPA, Negative Percent Agreement NSAIDs, Non-Steroidal Anti-Inflammatory Drugs Pnpp, p -Nitrophenylphosphate PPA, Positive Percent Agreement PPT, Prick-Prick Test Sige, specific IgE RAST, Radio Allergo Sorbent Test SCAR, severe cutaneous adverse drug reactions SPT, Skin prick test W/v, weight /volume |
| description |
Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2 2020-01-01 2020 2020-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/227656 https://dx.doi.org/urn:doi:10.1016/j.waojou.2019.100080 |
| url |
https://ddd.uab.cat/record/227656 https://dx.doi.org/urn:doi:10.1016/j.waojou.2019.100080 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.rights.openaire.fl_str_mv |
info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.source.none.fl_str_mv |
reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
| instname_str |
Universitat Autònoma de Barcelona |
| reponame_str |
Dipòsit Digital de Documents de la UAB |
| collection |
Dipòsit Digital de Documents de la UAB |
| repository.name.fl_str_mv |
|
| repository.mail.fl_str_mv |
|
| _version_ |
1869417561519554560 |
| spelling |
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paperAnsotegui Zubeldia, Ignacio Javier|||0000-0002-6942-1511Melioli, GiovanniCanonica, G. Walter|||0000-0001-8467-2557Caraballo, LuisVilla, ElisaEbisawa, Motohiro|||0000-0003-4117-558XPassalacqua, Giovanni|||0000-0002-5139-3604Savi, EleonoraEbo, Didier|||0000-0003-0672-7529Gómez, R. MaximilianoLuengo Sánchez, Olga|||0000-0002-8905-2776Oppenheimer, John J.Jensen-Jarolim, ErikaFischer, David A.Haahtela, Tari|||0000-0003-4757-2156Antila, MarttiBousquet, Jean|||0000-0002-4061-4766Cardona, Victoria|||0000-0003-2197-9767Chiang, Wen ChinDemoly, Pascal|||0000-0001-7827-7964DuBuske, Lawrence M.Ferrer Puga, MartaGerth van Wijk, RoyGonzález Díaz, Sandra NoraGonzalez-Estrada, AlexeiJares, E. J.|||0000-0001-9411-0582Kalpaklioğlu, Ayse FüsunKase Tanno, LucianaKowalski, Marek L.Ledford, Dennis K.Monge Ortega, Olga PatriciaMorais Almeida, MárioPfaar, Oliver|||0000-0003-4374-9639Poulsen, Lars K.Pawankar, RubyRenz, Harald E.Romano, Antonino G.Rosário Filho, Nelson A.Rosenwasser, LannySánchez Borges, Mario|||0000-0002-9308-6418Scala, Enrico|||0000-0002-9391-9168Senna, Gian-EnricoSisul, Juan CarlosTang, Mimi L. K.Thong, Bernard Yu-HorValenta, RudolfWood, Robert A.Zuberbier, Torsten|||0000-0002-1466-8875IgEAllergyIn vitro testsSkin testsDiagnostic strategiesAAAAI, American Academy of Allergy Asthma and ImmunologyABA, Allergen Bead ArrayACAAI, American College of Allergy Asthma and ImmunologyAIT, allergen immunotherapyAEC, Allergen Exposure ChambersAnti-IgE, Antibody against IgEAP, Alkaline PhosphataseAU/mL, Allergenic Units milliLiterBAT, Basophil Activation TestBAU/mL, Biologic Allergenic Units milliLiterCaFE, Calibrated Fluorescence EnhancementCBA, Cytometric Bead ArrayCCD, Cross-reactive Carbohydrate DeterminantsCDER, Center for Drug Evaluation and Research (USA)CL, ChemiluminescenceDBPCFC, Double-Blind Placebo-Controlled Food ChallengeEAACI, European Academy of Allergy and ImmunologyEIA, Enzyme Immune AssayELISA, Enzyme Linked Immuno Sorbent AnalysisEMEA, European MEdicine AgenciesENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3FACS, Fluorescence-Activated Cell SortingFDA, Food and Drug Administration (U.S. Department of Health and Human Services)FEIA, Fluorescent Enzyme ImmunoassaysFcεRI, High affinity IgE receptorH1, Histamine 1 receptorH2, Histamine 2 receptorHPO, Horseradish PeroxidaseIDT, Intradermal TestIgE, immunoglobulin EISAC, Immuno-Solid phase Allergen ChipIUIS, International Union of Immunological SocietiesIVD, in vitro diagnostic toolKu/l, kilo Units of Allergen/Liter for allergen-specific IgE antibody assaysLAMP-3, Lysosomal-Associated Membrane ProteinMab, Monoclonal AntibodyMRGPRX2, Mas-related G protein receptor 2MBAD, Molecule Based Allergy DiagnosticsNIH, National Institutes of Health (USA)NMBAs, NeuroMuscular Blocking AgentsNPA, Negative Percent AgreementNSAIDs, Non-Steroidal Anti-Inflammatory DrugsPnpp, p -NitrophenylphosphatePPA, Positive Percent AgreementPPT, Prick-Prick TestSige, specific IgERAST, Radio Allergo Sorbent TestSCAR, severe cutaneous adverse drug reactionsSPT, Skin prick testW/v, weight /volumeCurrently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen.Universitat Autònoma de Barcelona 22020-01-0120202020-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/227656https://dx.doi.org/urn:doi:10.1016/j.waojou.2019.100080reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2276562026-06-06T12:50:31Z |
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15.300724 |