Immunohistochemical analysis of PrPres using different antibodies

Representative brain sections from transgenic mice 195Y and 195H, inoculated and not inoculated, were stained with anti-PrP antibodies: Saf-61 (A) and 6H4 (B). No PrPres signal was detected in any of the experimental groups, whereas a clear positive signal was observed in RML-infected CD1 mice used...

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Detalles Bibliográficos
Autores: Torres, Juan María, Marín-Moreno, Alba, Espinosa, Juan Carlos, Canoyra, Sara, Burato, Anna, Ciullini, Arianna, De Luca, Chiara Maria Giulia, Bistaffa, Edoardo, Moda, F., Legname, Giuseppe
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/406763
Acceso en línea:http://hdl.handle.net/10261/406763
Access Level:acceso abierto
Palabra clave:Neurodegenerative disorders caused
Mice expressing wild
Copper may play
div >< p
vivo </
tga20 </
Spongiform encephalopathy
Spongiform degeneration
Region located
Prion protein
Prion diseases
Prion disease
Octapeptide repeats
Misfolded isoform
Histidine 95
Functional implication
Copper binding
Cellular form
Brain homogenate
Binding site
100 Days
Descripción
Sumario:Representative brain sections from transgenic mice 195Y and 195H, inoculated and not inoculated, were stained with anti-PrP antibodies: Saf-61 (A) and 6H4 (B). No PrPres signal was detected in any of the experimental groups, whereas a clear positive signal was observed in RML-infected CD1 mice used as positive control.