Persulfidation is the mechanism underlying sulfide-signaling of autophagy
In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups o...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de Sevilla (US) |
| Repositorio: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:idus.us.es:11441/112196 |
| Acceso en línea: | https://hdl.handle.net/11441/112196 https://doi.org/10.1080/15548627.2021.1936357 |
| Access Level: | acceso abierto |
| Palabra clave: | Arabidopsis GAPDH Hydrogen sulfide Persulfidated cysteine Posttranslational modification Stress |
| Sumario: | In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism. |
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