Persulfidation is the mechanism underlying sulfide-signaling of autophagy
In this commentary, we highlight the findings described in a recent paper regarding the mechanismof H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiolgroups of...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/304139 |
| Acceso en línea: | http://hdl.handle.net/10261/304139 |
| Access Level: | acceso abierto |
| Palabra clave: | Arabidopsis GAPDH Hydrogen sulfide Persulfidated cysteine Posttranslational modification Stress |
| Sumario: | In this commentary, we highlight the findings described in a recent paper regarding the mechanismof H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiolgroups of cysteine residues to form persulfides is a conserved molecular mechanism. |
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