Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study

To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered whe...

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Autores: Benaiges Foix, David, Bisbe Maria, Pedro-Botet, Juan, Vargas-Machuca, Aleix de, Ramón Moros, José Manuel, Pera Román, Manuel, Villatoro Moreno, Montserrat, Fontane Francia, Laia, Julià, Helena, Climent, Elisenda, Castañer, Olga, Flores Le Roux, Juana Antonia, Goday Arnó, Albert
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/48649
Acceso en línea:http://hdl.handle.net/10230/48649
http://dx.doi.org/10.3390/jcm9103193
Access Level:acceso abierto
Palabra clave:Bariatric surgery
Gastric bypass
Obesity
Severe obesity
Sleeve gastrectomy
Weight loss
Weight regain
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spelling Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up studyBenaiges Foix, DavidBisbe MariaPedro-Botet, JuanVargas-Machuca, Aleix deRamón Moros, José ManuelPera Román, ManuelVillatoro Moreno, MontserratFontane Francia, LaiaJulià, HelenaCliment, ElisendaCastañer, OlgaFlores Le Roux, Juana AntoniaGoday Arnó, AlbertBariatric surgeryGastric bypassObesitySevere obesitySleeve gastrectomyWeight lossWeight regainTo ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered when 5-year excess weight loss was <50%. Results: Forty-three (20.3%) of the 212 included patients were mid-term poor WL responders. They showed an improvement in all metabolic markers at 2 years, except for total cholesterol. This improvement with respect to baseline was maintained at 5 years for plasma glucose, HbA1c, HOMA, HDL and diastolic blood pressure; however, LDL cholesterol, triglycerides and systolic blood pressure were similar to presurgical values. Comorbidity remission rates were comparable to those obtained in the good WL group except for hypercholesterolaemia (45.8% vs. poor WL, p = 0.005). On multivariate analysis, lower baseline HDL cholesterol levels, advanced age and lower preoperative weight loss were independently associated with poor mid-term WL. Conclusions: Although that 1 in 5 patients presented suboptimal WL 5 years after bariatric surgery, other important metabolic benefits were maintained.MDPI202120212020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/48649http://dx.doi.org/10.3390/jcm9103193reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglés© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/486492026-06-12T07:21:37Z
dc.title.none.fl_str_mv Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
title Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
spellingShingle Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
Benaiges Foix, David
Bariatric surgery
Gastric bypass
Obesity
Severe obesity
Sleeve gastrectomy
Weight loss
Weight regain
title_short Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
title_full Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
title_fullStr Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
title_full_unstemmed Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
title_sort Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study
dc.creator.none.fl_str_mv Benaiges Foix, David
Bisbe Maria
Pedro-Botet, Juan
Vargas-Machuca, Aleix de
Ramón Moros, José Manuel
Pera Román, Manuel
Villatoro Moreno, Montserrat
Fontane Francia, Laia
Julià, Helena
Climent, Elisenda
Castañer, Olga
Flores Le Roux, Juana Antonia
Goday Arnó, Albert
author Benaiges Foix, David
author_facet Benaiges Foix, David
Bisbe Maria
Pedro-Botet, Juan
Vargas-Machuca, Aleix de
Ramón Moros, José Manuel
Pera Román, Manuel
Villatoro Moreno, Montserrat
Fontane Francia, Laia
Julià, Helena
Climent, Elisenda
Castañer, Olga
Flores Le Roux, Juana Antonia
Goday Arnó, Albert
author_role author
author2 Bisbe Maria
Pedro-Botet, Juan
Vargas-Machuca, Aleix de
Ramón Moros, José Manuel
Pera Román, Manuel
Villatoro Moreno, Montserrat
Fontane Francia, Laia
Julià, Helena
Climent, Elisenda
Castañer, Olga
Flores Le Roux, Juana Antonia
Goday Arnó, Albert
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Bariatric surgery
Gastric bypass
Obesity
Severe obesity
Sleeve gastrectomy

Weight loss
Weight regain
topic Bariatric surgery
Gastric bypass
Obesity
Severe obesity
Sleeve gastrectomy
Weight loss
Weight regain
description To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered when 5-year excess weight loss was <50%. Results: Forty-three (20.3%) of the 212 included patients were mid-term poor WL responders. They showed an improvement in all metabolic markers at 2 years, except for total cholesterol. This improvement with respect to baseline was maintained at 5 years for plasma glucose, HbA1c, HOMA, HDL and diastolic blood pressure; however, LDL cholesterol, triglycerides and systolic blood pressure were similar to presurgical values. Comorbidity remission rates were comparable to those obtained in the good WL group except for hypercholesterolaemia (45.8% vs. poor WL, p = 0.005). On multivariate analysis, lower baseline HDL cholesterol levels, advanced age and lower preoperative weight loss were independently associated with poor mid-term WL. Conclusions: Although that 1 in 5 patients presented suboptimal WL 5 years after bariatric surgery, other important metabolic benefits were maintained.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/48649
http://dx.doi.org/10.3390/jcm9103193
url http://hdl.handle.net/10230/48649
http://dx.doi.org/10.3390/jcm9103193
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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