Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it

Assessing age-related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several largescale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcript...

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Bibliographic Details
Authors: Lynch, Cian J., Serrano Marugán, Manuel
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/189144
Online Access:https://hdl.handle.net/2445/189144
Access Level:Open access
Keyword:Genòmica
Cromatina
Genomics
Chromatin
Description
Summary:Assessing age-related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several largescale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings. © 2022 The Authors. Published under the terms of the CC BY 4.0 license.