Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it

Assessing age-related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several largescale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcript...

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Detalles Bibliográficos
Autores: Lynch, Cian J., Serrano Marugán, Manuel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/189144
Acceso en línea:https://hdl.handle.net/2445/189144
Access Level:acceso abierto
Palabra clave:Genòmica
Cromatina
Genomics
Chromatin
Descripción
Sumario:Assessing age-related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several largescale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings. © 2022 The Authors. Published under the terms of the CC BY 4.0 license.