Automatic Assessment of the 2-Minute Walk Distance for Remote Monitoring of People with Multiple Sclerosis

The aim of this study was to investigate the feasibility of automatically assessing the 2-Minute Walk Distance (2MWD) for monitoring people with multiple sclerosis (pwMS). For 154 pwMS, MS-related clinical outcomes as well as the 2MWDs as evaluated by clinicians and derived from accelerometer data w...

Descripción completa

Detalles Bibliográficos
Autores: Kontaxis, Spyridon|||0000-0002-1297-0691, Laporta, Estela|||0000-0001-6776-8522, Garcia, Esther|||0000-0003-3997-493X, Martinis, Matteo, Leocani, Letizia|||0000-0001-9326-6753, Roselli, Lucia, Buron, Mathias Due|||0000-0003-1260-1156, Guerrero, Ana Isabel|||0000-0001-5891-2123, Zabalza, Ana|||0000-0003-3860-5251, Cummins, Nicholas, Vairavan, Srinivasan, Hotopf, Matthew|||0000-0002-3980-4466, Dobson, Richard James Butler|||0000-0003-4224-9245, Narayan, Vaibhav A., La Porta, Maria Libera, Costa, Gloria Dalla, Magyari, Melinda|||0000-0002-0972-5222, Sørensen, Per S|||0000-0002-2818-3780, Nos, Carlos|||0000-0002-3830-4910, Bailón, Raquel|||0000-0003-1272-0550, Comi, Giancarlo|||0000-0002-6989-1054
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:284678
Acceso en línea:https://ddd.uab.cat/record/284678
https://dx.doi.org/urn:doi:10.3390/s23136017
Access Level:acceso abierto
Palabra clave:Accelerometer sensor
Disability level
Fatigue severity
Walk tests
Wearable device
Descripción
Sumario:The aim of this study was to investigate the feasibility of automatically assessing the 2-Minute Walk Distance (2MWD) for monitoring people with multiple sclerosis (pwMS). For 154 pwMS, MS-related clinical outcomes as well as the 2MWDs as evaluated by clinicians and derived from accelerometer data were collected from a total of 323 periodic clinical visits. Accelerometer data from a wearable device during 100 home-based 2MWD assessments were also acquired. The error in estimating the 2MWD was validated for walk tests performed at hospital, and then the correlation (r) between clinical outcomes and home-based 2MWD assessments was evaluated. Robust performance in estimating the 2MWD from the wearable device was obtained, yielding an error of less than 10% in about two-thirds of clinical visits. Correlation analysis showed that there is a strong association between the actual and the estimated 2MWD obtained either at hospital (r = 0.71) or at home (r = 0.58). Furthermore, the estimated 2MWD exhibits moderate-to-strong correlation with various MS-related clinical outcomes, including disability and fatigue severity scores. Automatic assessment of the 2MWD in pwMS is feasible with the usage of a consumer-friendly wearable device in clinical and non-clinical settings. Wearable devices can also enhance the assessment of MS-related clinical outcomes.

Similares en LA Referencia