Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa

Membrives, Sonia|||0000-0002-0439-7936; López-Solà, Marina|||0000-0002-5517-2665; Fernández Aranda, Fernando|||0000-0002-2968-9898; Sánchez Díaz, Isabel María|||0000-0001-5874-8204; Martínez-Zalacaín, Ignacio|||0000-0002-4036-0284; Palao, Diego|||0000-0002-3323-6568; Pujol Nuez, Jesús|||0000-0002-9946-4547; Menchón Magriñá, José Manuel|||0000-0002-6231-6524; Davey, Chris G.; Harrison, Ben J.; Keating, Charlotte; Rossell, Susan L.; Oliva, Joan Carles|||0000-0003-1273-2746; Soriano-Mas, Carles|||0000-0003-4574-6597; Cardoner, Narcís|||0000-0001-9633-0888; Via, Esther|||0000-0002-2331-3232

Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa

Objective: Research suggests abnormalities in reward-based processes in anorexia nervosa (AN). However, few studies have explored if such alterations might be associated with different temporal activation patterns. This study aims to characterize alterations in time-dependent processes in the ventra...

Descripción completa

Detalles Bibliográficos
Autores:	Membrives, Sonia\|\|\|0000-0002-0439-7936, López-Solà, Marina\|\|\|0000-0002-5517-2665, Fernández Aranda, Fernando\|\|\|0000-0002-2968-9898, Sánchez Díaz, Isabel María\|\|\|0000-0001-5874-8204, Martínez-Zalacaín, Ignacio\|\|\|0000-0002-4036-0284, Palao, Diego\|\|\|0000-0002-3323-6568, Pujol Nuez, Jesús\|\|\|0000-0002-9946-4547, Menchón Magriñá, José Manuel\|\|\|0000-0002-6231-6524, Davey, Chris G., Harrison, Ben J., Keating, Charlotte, Rossell, Susan L., Oliva, Joan Carles\|\|\|0000-0003-1273-2746, Soriano-Mas, Carles\|\|\|0000-0003-4574-6597, Cardoner, Narcís\|\|\|0000-0001-9633-0888, Via, Esther\|\|\|0000-0002-2331-3232
Tipo de recurso:	artículo
Fecha de publicación:	2021
País:	España
Institución:	Universitat Autònoma de Barcelona
Repositorio:	Dipòsit Digital de Documents de la UAB
Idioma:	inglés
OAI Identifier:	oai:ddd.uab.cat:311424
Acceso en línea:	https://ddd.uab.cat/record/311424 https://dx.doi.org/urn:doi:10.1002/eat.23604
Access Level:	acceso abierto
Palabra clave:	Anorexia nervosa Functional magnetic resonance imaging Reward system Social reward Ventral striatum

id	ES_b1bd2ec6409abff16074b05c4a855dd2
oai_identifier_str	oai:ddd.uab.cat:311424
network_acronym_str	ES
network_name_str	España
repository_id_str
spelling	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosaA functional magnetic resonance imaging exploratory studyMembrives, Sonia\|\|\|0000-0002-0439-7936López-Solà, Marina\|\|\|0000-0002-5517-2665Fernández Aranda, Fernando\|\|\|0000-0002-2968-9898Sánchez Díaz, Isabel María\|\|\|0000-0001-5874-8204Martínez-Zalacaín, Ignacio\|\|\|0000-0002-4036-0284Palao, Diego\|\|\|0000-0002-3323-6568Pujol Nuez, Jesús\|\|\|0000-0002-9946-4547Menchón Magriñá, José Manuel\|\|\|0000-0002-6231-6524Davey, Chris G.Harrison, Ben J.Keating, CharlotteRossell, Susan L.Oliva, Joan Carles\|\|\|0000-0003-1273-2746Soriano-Mas, Carles\|\|\|0000-0003-4574-6597Cardoner, Narcís\|\|\|0000-0001-9633-0888Via, Esther\|\|\|0000-0002-2331-3232Anorexia nervosaFunctional magnetic resonance imagingReward systemSocial rewardVentral striatumObjective: Research suggests abnormalities in reward-based processes in anorexia nervosa (AN). However, few studies have explored if such alterations might be associated with different temporal activation patterns. This study aims to characterize alterations in time-dependent processes in the ventral striatum (VS) during social feedback in AN using functional magnetic resonance imaging (fMRI). Method: Twenty women with restrictive-subtype AN and 20 age-matched healthy controls (HC) underwent a social judgment experimental fMRI task. Temporal VS hemodynamic responses were extracted in SPM for each participant and each social condition (acceptance/rejection). Results: Compared with age-matched HC, patients with AN showed a significant time by group interaction of peak VS response throughout the task, with a progressive blunting of peak activation responses, accompanied by a progressive increase in baseline activity levels over time. Discussion: The results suggest an attenuated response pattern to repetitive social rejection in the VS in patients with AN, together with a difficulty in returning to baseline. The information obtained from this study will guide future, design-specific studies to further explore alterations temporal dynamics. 22021-01-0120212021-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/311424https://dx.doi.org/urn:doi:10.1002/eat.23604reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengInstituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI17/01167Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI20/00132open accesshttp://purl.org/coar/access_right/c_abf2Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.https://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3114242026-06-06T12:50:31Z
dc.title.none.fl_str_mv	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa A functional magnetic resonance imaging exploratory study
title	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
spellingShingle	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa Membrives, Sonia\|\|\|0000-0002-0439-7936 Anorexia nervosa Functional magnetic resonance imaging Reward system Social reward Ventral striatum
title_short	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
title_full	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
title_fullStr	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
title_full_unstemmed	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
title_sort	Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa
dc.creator.none.fl_str_mv	Membrives, Sonia\|\|\|0000-0002-0439-7936 López-Solà, Marina\|\|\|0000-0002-5517-2665 Fernández Aranda, Fernando\|\|\|0000-0002-2968-9898 Sánchez Díaz, Isabel María\|\|\|0000-0001-5874-8204 Martínez-Zalacaín, Ignacio\|\|\|0000-0002-4036-0284 Palao, Diego\|\|\|0000-0002-3323-6568 Pujol Nuez, Jesús\|\|\|0000-0002-9946-4547 Menchón Magriñá, José Manuel\|\|\|0000-0002-6231-6524 Davey, Chris G. Harrison, Ben J. Keating, Charlotte Rossell, Susan L. Oliva, Joan Carles\|\|\|0000-0003-1273-2746 Soriano-Mas, Carles\|\|\|0000-0003-4574-6597 Cardoner, Narcís\|\|\|0000-0001-9633-0888 Via, Esther\|\|\|0000-0002-2331-3232
author	Membrives, Sonia\|\|\|0000-0002-0439-7936
author_facet	Membrives, Sonia\|\|\|0000-0002-0439-7936 López-Solà, Marina\|\|\|0000-0002-5517-2665 Fernández Aranda, Fernando\|\|\|0000-0002-2968-9898 Sánchez Díaz, Isabel María\|\|\|0000-0001-5874-8204 Martínez-Zalacaín, Ignacio\|\|\|0000-0002-4036-0284 Palao, Diego\|\|\|0000-0002-3323-6568 Pujol Nuez, Jesús\|\|\|0000-0002-9946-4547 Menchón Magriñá, José Manuel\|\|\|0000-0002-6231-6524 Davey, Chris G. Harrison, Ben J. Keating, Charlotte Rossell, Susan L. Oliva, Joan Carles\|\|\|0000-0003-1273-2746 Soriano-Mas, Carles\|\|\|0000-0003-4574-6597 Cardoner, Narcís\|\|\|0000-0001-9633-0888 Via, Esther\|\|\|0000-0002-2331-3232
author_role	author
author2	López-Solà, Marina\|\|\|0000-0002-5517-2665 Fernández Aranda, Fernando\|\|\|0000-0002-2968-9898 Sánchez Díaz, Isabel María\|\|\|0000-0001-5874-8204 Martínez-Zalacaín, Ignacio\|\|\|0000-0002-4036-0284 Palao, Diego\|\|\|0000-0002-3323-6568 Pujol Nuez, Jesús\|\|\|0000-0002-9946-4547 Menchón Magriñá, José Manuel\|\|\|0000-0002-6231-6524 Davey, Chris G. Harrison, Ben J. Keating, Charlotte Rossell, Susan L. Oliva, Joan Carles\|\|\|0000-0003-1273-2746 Soriano-Mas, Carles\|\|\|0000-0003-4574-6597 Cardoner, Narcís\|\|\|0000-0001-9633-0888 Via, Esther\|\|\|0000-0002-2331-3232
author2_role	author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Anorexia nervosa Functional magnetic resonance imaging Reward system Social reward Ventral striatum
topic	Anorexia nervosa Functional magnetic resonance imaging Reward system Social reward Ventral striatum
description	Objective: Research suggests abnormalities in reward-based processes in anorexia nervosa (AN). However, few studies have explored if such alterations might be associated with different temporal activation patterns. This study aims to characterize alterations in time-dependent processes in the ventral striatum (VS) during social feedback in AN using functional magnetic resonance imaging (fMRI). Method: Twenty women with restrictive-subtype AN and 20 age-matched healthy controls (HC) underwent a social judgment experimental fMRI task. Temporal VS hemodynamic responses were extracted in SPM for each participant and each social condition (acceptance/rejection). Results: Compared with age-matched HC, patients with AN showed a significant time by group interaction of peak VS response throughout the task, with a progressive blunting of peak activation responses, accompanied by a progressive increase in baseline activity levels over time. Discussion: The results suggest an attenuated response pattern to repetitive social rejection in the VS in patients with AN, together with a difficulty in returning to baseline. The information obtained from this study will guide future, design-specific studies to further explore alterations temporal dynamics.
publishDate	2021
dc.date.none.fl_str_mv	2 2021-01-01 2021 2021-01-01
dc.type.none.fl_str_mv	Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://ddd.uab.cat/record/311424 https://dx.doi.org/urn:doi:10.1002/eat.23604
url	https://ddd.uab.cat/record/311424 https://dx.doi.org/urn:doi:10.1002/eat.23604
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.relation.none.fl_str_mv	Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI17/01167 Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI20/00132
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.source.none.fl_str_mv	reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona
instname_str	Universitat Autònoma de Barcelona
reponame_str	Dipòsit Digital de Documents de la UAB
collection	Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869416975269101568
score	15,811543

Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa

Similares en LA Referencia