Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI

Extraordinary properties are often described for 2D nanocomposites involving graphene flakes and a second component selected from particles or fibers. From this family of hybrid materials, this study is centered on composites based on graphene oxide (GO), a multifunctional oxygenated version of grap...

Descripción completa

Detalles Bibliográficos
Autores: Borrás, Alejandro, Fraile, Julio, Rosado, Albert, Marbán Calzón, Gregorio, Tobias, Gerard, López Periago, Ana M., Domingo Pascual, M. Concepción
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/230846
Acceso en línea:http://hdl.handle.net/10261/230846
Access Level:acceso abierto
Palabra clave:Graphene oxide
Aerogeles
Supercritical CO2
SPION
Magnetic resonance imaging
id ES_b0d74cbe33b7be2bd424dac176fb73a2
oai_identifier_str oai:digital.csic.es:10261/230846
network_acronym_str ES
network_name_str España
repository_id_str
spelling Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRIBorrás, AlejandroFraile, JulioRosado, AlbertMarbán Calzón, GregorioTobias, GerardLópez Periago, Ana M.Domingo Pascual, M. ConcepciónGraphene oxideAerogelesSupercritical CO2SPIONMagnetic resonance imagingExtraordinary properties are often described for 2D nanocomposites involving graphene flakes and a second component selected from particles or fibers. From this family of hybrid materials, this study is centered on composites based on graphene oxide (GO), a multifunctional oxygenated version of graphene, and superparamagnetic iron oxide nanoparticles (SPIONs), with applications as contrast agents in magnetic resonance imaging (MRI). The research focuses on the loading of SPIONs onto a GO surface via a simple one-pot supercritical CO2 technique. The developed all-green synthesis approach allows the preparation of hybrid materials shaped into aerogels with large mesoporosity. The use of coated and uncoated components in the aerogel composites is analyzed with emphasis in the significance of the arrangement of the NPs into clusters on the GO surface and related with the magnetic properties. The development of composites involving organic coating has been widely studied to pursue the double objective of increasing NP/GO conjugation and improving the system biocompatibility. Extensive structural and functional characterization is carried out to understand the behavior of composites toward their performance as contrast agents in MRI.This work was financed by the Spanish National Plan of Research with projects CTQ2017-83632 and MAT2017-86616-R. C.D., G.T., A.B, J.F., and A.M.L.P. acknowledge the financial support from the Spanish MEC, through the Severo Ochoa Program for Centres of Excellence in R&D (SEV-2015-0496). This work (A.B.) has been done in the framework of the doctoral program “Chemistry” of the Universitat Autònoma de Barcelona. A.M.L.P. acknowledges the RyC-2012-11588 contract. A.B. acknowledges the FPI grant.Peer reviewedAmerican Chemical SocietyMinisterio de Economía y Competitividad (España)Ministerio de Ciencia, Innovación y Universidades (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202120212020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/230846reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/CTQ2017-83632info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/MAT2017-86616-Rinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SEV-2015-0496http://dx.doi.org/10.1021/acssuschemeng.0c00149Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2308462026-05-22T06:33:51Z
dc.title.none.fl_str_mv Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
title Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
spellingShingle Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
Borrás, Alejandro
Graphene oxide
Aerogeles
Supercritical CO2
SPION
Magnetic resonance imaging
title_short Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
title_full Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
title_fullStr Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
title_full_unstemmed Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
title_sort Green and Solvent-Free Supercritical CO2-Assisted Production of Superparamagnetic Graphene Oxide Aerogels: Application as a Superior Contrast Agent in MRI
dc.creator.none.fl_str_mv Borrás, Alejandro
Fraile, Julio
Rosado, Albert
Marbán Calzón, Gregorio
Tobias, Gerard
López Periago, Ana M.
Domingo Pascual, M. Concepción
author Borrás, Alejandro
author_facet Borrás, Alejandro
Fraile, Julio
Rosado, Albert
Marbán Calzón, Gregorio
Tobias, Gerard
López Periago, Ana M.
Domingo Pascual, M. Concepción
author_role author
author2 Fraile, Julio
Rosado, Albert
Marbán Calzón, Gregorio
Tobias, Gerard
López Periago, Ana M.
Domingo Pascual, M. Concepción
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Ministerio de Ciencia, Innovación y Universidades (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Graphene oxide
Aerogeles
Supercritical CO2
SPION
Magnetic resonance imaging
topic Graphene oxide
Aerogeles
Supercritical CO2
SPION
Magnetic resonance imaging
description Extraordinary properties are often described for 2D nanocomposites involving graphene flakes and a second component selected from particles or fibers. From this family of hybrid materials, this study is centered on composites based on graphene oxide (GO), a multifunctional oxygenated version of graphene, and superparamagnetic iron oxide nanoparticles (SPIONs), with applications as contrast agents in magnetic resonance imaging (MRI). The research focuses on the loading of SPIONs onto a GO surface via a simple one-pot supercritical CO2 technique. The developed all-green synthesis approach allows the preparation of hybrid materials shaped into aerogels with large mesoporosity. The use of coated and uncoated components in the aerogel composites is analyzed with emphasis in the significance of the arrangement of the NPs into clusters on the GO surface and related with the magnetic properties. The development of composites involving organic coating has been widely studied to pursue the double objective of increasing NP/GO conjugation and improving the system biocompatibility. Extensive structural and functional characterization is carried out to understand the behavior of composites toward their performance as contrast agents in MRI.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/230846
url http://hdl.handle.net/10261/230846
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/CTQ2017-83632
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/MAT2017-86616-R
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SEV-2015-0496
http://dx.doi.org/10.1021/acssuschemeng.0c00149
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416860499312640
score 15,811543

Similares en LA Referencia