Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain

Hepatitis E virus (HEV), shared by humans, domestic animals, and wildlife, is an emerging global public health threat. Because wild boars are a major reservoir of HEV, the new zoonotic interfaces resulting from wild boar population increase and synurbization significantly contribute to increasing th...

Descripción completa

Detalles Bibliográficos
Autores: Ruiz-Ponsell, Laia, Monastiri, Abir, López-Roig, Marc, Sauleda, Silvia, Bes, Marta, Mentaberre, Gregorio, Escobar-González, María, Costafreda Salvany, M. Isabel (Maria Isabel), López Olvera, Jorge R., Serra Cobo, Jordi
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/216957
Acceso en línea:https://hdl.handle.net/2445/216957
Access Level:acceso abierto
Palabra clave:Salut pública
Virus de l'hepatitis E
Senglar
Public health
Hepatitis E virus
Wild boar
id ES_b03f4e943d64c2e825fdcb8686281119
oai_identifier_str oai:recercat.cat:2445/216957
network_acronym_str ES
network_name_str España
repository_id_str
spelling Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, SpainRuiz-Ponsell, LaiaMonastiri, AbirLópez-Roig, MarcSauleda, SilviaBes, MartaMentaberre, GregorioEscobar-González, MaríaCostafreda Salvany, M. Isabel (Maria Isabel)López Olvera, Jorge R.Serra Cobo, JordiSalut públicaVirus de l'hepatitis ESenglarPublic healthHepatitis E virusWild boarHepatitis E virus (HEV), shared by humans, domestic animals, and wildlife, is an emerging global public health threat. Because wild boars are a major reservoir of HEV, the new zoonotic interfaces resulting from wild boar population increase and synurbization significantly contribute to increasing the risk of zoonotic transmission of HEV. This study characterizes HEV strains of synurbic wild boars and assesses their relationship with sympatric human and domestic swine HEV strains. We analyzed the faeces of 312 synurbic wild boars collected from 2016 to 2021 in the Barcelona Metropolitan Area (BMA), where there is a high density of wild boars, and found 7 HEV-positive samples among those collected between 2019 and 2020. The molecular analysis of these isolates, along with 6 additional wild boar HEV isolates from a previous study, allowed us to establish a close phylogenetic relationship between these HEV strains and human HEV isolates from sympatric blood donors and domestic pigs from Catalonia. HEV-positive wild boar samples belonged to piglet, juvenile and yearling individuals, but not adults, indicating the endemic maintenance of HEV in the wild boar population of the BMA by naïve young individuals. All wild boar HEV isolates in this study classified within HEV genotype 3. The results show, for the first time, a close molecular similarity between the HEV strains endemically maintained by the synurbic wild boars in the BMA and citizens from the same area and period. The data could also indicate that HEV infection presents a seasonal and interannual variability in wild boars of BMA. Further investigation is required to unveil the HEV transmission routes between synurbic wild boars and sympatric citizens. These findings can serve in other synurbic wildlife-human interfaces throughout the world.Elsevier B.V.2024202420242024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion7 p.application/pdfhttps://hdl.handle.net/2445/216957Articles publicats en revistes (Genètica, Microbiologia i Estadística)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1016/j.scitotenv.2024.176871Science of the Total Environment, 2024, vol. 955, p. 1-7https://doi.org/10.1016/j.scitotenv.2024.176871cc-by-nc-nd (c) Ruiz-Ponsell, Laia et al., 2024http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2169572026-05-29T05:05:01Z
dc.title.none.fl_str_mv Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
title Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
spellingShingle Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
Ruiz-Ponsell, Laia
Salut pública
Virus de l'hepatitis E
Senglar
Public health
Hepatitis E virus
Wild boar
title_short Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
title_full Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
title_fullStr Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
title_full_unstemmed Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
title_sort Endemic maintenance of human-related hepatitis E virus strains in synurbic wild boars, Barcelona Metropolitan Area, Spain
dc.creator.none.fl_str_mv Ruiz-Ponsell, Laia
Monastiri, Abir
López-Roig, Marc
Sauleda, Silvia
Bes, Marta
Mentaberre, Gregorio
Escobar-González, María
Costafreda Salvany, M. Isabel (Maria Isabel)
López Olvera, Jorge R.
Serra Cobo, Jordi
author Ruiz-Ponsell, Laia
author_facet Ruiz-Ponsell, Laia
Monastiri, Abir
López-Roig, Marc
Sauleda, Silvia
Bes, Marta
Mentaberre, Gregorio
Escobar-González, María
Costafreda Salvany, M. Isabel (Maria Isabel)
López Olvera, Jorge R.
Serra Cobo, Jordi
author_role author
author2 Monastiri, Abir
López-Roig, Marc
Sauleda, Silvia
Bes, Marta
Mentaberre, Gregorio
Escobar-González, María
Costafreda Salvany, M. Isabel (Maria Isabel)
López Olvera, Jorge R.
Serra Cobo, Jordi
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Salut pública
Virus de l'hepatitis E
Senglar
Public health
Hepatitis E virus
Wild boar
topic Salut pública
Virus de l'hepatitis E
Senglar
Public health
Hepatitis E virus
Wild boar
description Hepatitis E virus (HEV), shared by humans, domestic animals, and wildlife, is an emerging global public health threat. Because wild boars are a major reservoir of HEV, the new zoonotic interfaces resulting from wild boar population increase and synurbization significantly contribute to increasing the risk of zoonotic transmission of HEV. This study characterizes HEV strains of synurbic wild boars and assesses their relationship with sympatric human and domestic swine HEV strains. We analyzed the faeces of 312 synurbic wild boars collected from 2016 to 2021 in the Barcelona Metropolitan Area (BMA), where there is a high density of wild boars, and found 7 HEV-positive samples among those collected between 2019 and 2020. The molecular analysis of these isolates, along with 6 additional wild boar HEV isolates from a previous study, allowed us to establish a close phylogenetic relationship between these HEV strains and human HEV isolates from sympatric blood donors and domestic pigs from Catalonia. HEV-positive wild boar samples belonged to piglet, juvenile and yearling individuals, but not adults, indicating the endemic maintenance of HEV in the wild boar population of the BMA by naïve young individuals. All wild boar HEV isolates in this study classified within HEV genotype 3. The results show, for the first time, a close molecular similarity between the HEV strains endemically maintained by the synurbic wild boars in the BMA and citizens from the same area and period. The data could also indicate that HEV infection presents a seasonal and interannual variability in wild boars of BMA. Further investigation is required to unveil the HEV transmission routes between synurbic wild boars and sympatric citizens. These findings can serve in other synurbic wildlife-human interfaces throughout the world.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/216957
url https://hdl.handle.net/2445/216957
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1016/j.scitotenv.2024.176871
Science of the Total Environment, 2024, vol. 955, p. 1-7
https://doi.org/10.1016/j.scitotenv.2024.176871
dc.rights.none.fl_str_mv cc-by-nc-nd (c) Ruiz-Ponsell, Laia et al., 2024
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc-nd (c) Ruiz-Ponsell, Laia et al., 2024
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Genètica, Microbiologia i Estadística)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416791860576256
score 15,812429

Similares en LA Referencia