Dual Catalytic Enantioconvergent Carbamoylation of Aziridines
Herein, we disclose an enantioconvergent carbamoylation of racemic aziridines enabled by a dual catalytic strategy. The method offers a new entry point to highly enantioenriched β-amino amides from simple precursors and is characterized by its broad applicability, even with challenging combinations....
| Autores: | , , , |
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| Formato: | conjunto de datos |
| Fecha de publicación: | 2026 |
| País: | España |
| Recursos: | Consorci de Serveis Universitaris de Catalunya (CSUC) |
| Repositorio: | CORA.Repositori de Dades de Recerca |
| OAI Identifier: | oai:dnet:cora.rdr____::ab5367e094242426675fdc1c505bb1c1 |
| Acesso em linha: | https://doi.org/10.34810/DATA3338 |
| Access Level: | acceso abierto |
| Palavra-chave: | Chemistry Catalysis Cross coupling Aziridines |
| Resumo: | Herein, we disclose an enantioconvergent carbamoylation of racemic aziridines enabled by a dual catalytic strategy. The method offers a new entry point to highly enantioenriched β-amino amides from simple precursors and is characterized by its broad applicability, even with challenging combinations. Preliminary studies with well-defined nickel complexes support a scenario via carbamoyl organometallic intermediates. |
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