Nickel-Catalyzed Site-Selective Intermolecular C(sp3)−H Amidation
A nickel-catalyzed site-selective intermolecular amidation of saturated C(sp3)–H bonds is reported. This mild protocol exhibits a predictable reactivity pattern to incorporate amide functions at C(sp3)–H sites adjacent to nitrogen and oxygen atoms in either cyclic or acyclic frameworks, thus offerin...
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Estado: | Versión aceptada para publicación |
| Data de publicação: | 2022 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositório: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2072/532804 |
| Acesso em linha: | http://hdl.handle.net/2072/532804 https://doi.org/10.1002/anie.202212983 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Química 00 |
| Resumo: | A nickel-catalyzed site-selective intermolecular amidation of saturated C(sp3)–H bonds is reported. This mild protocol exhibits a predictable reactivity pattern to incorporate amide functions at C(sp3)–H sites adjacent to nitrogen and oxygen atoms in either cyclic or acyclic frameworks, thus offering a complementary reactivity profile to existing oxidative-type processes or metal-catalyzed C(sp3)–N bond-forming reactions operating via two-electron manifolds. |
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