Incidentalomas suprarrenales: experiencia clínica en los hospitales de Castilla-La Mancha

ObjectiveThe management of incidentally discovered adrenal masses (incidentalomas) remains controversial. Our objective was to describe the demographic and clinical characteristics of a series of patients with adrenal incidentalomas attended in several hospitals of Castilla-La Mancha, and their diag...

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Detalles Bibliográficos
Autores: Lamas Oliveira, Cristina, Palma, Mercedes, Martín, David, Álvarez de Frutos, Visitación, López, María, Marco, Amparo
Tipo de recurso: artículo
Fecha de publicación:2009
País:España
Institución:Universidad de Castilla-La Mancha
Repositorio:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/33329
Acceso en línea:https://hdl.handle.net/10578/33329
Access Level:acceso abierto
Palabra clave:Adrenal incidentalomas
Feocromocitoma
Hiperaldosteronismo primario
Incidentalomas suprarrenales
Pheochromocytoma
Primary aldosteronism
Síndrome de Cushing subclínico
Subclinical Cushing syndrome
Descripción
Sumario:ObjectiveThe management of incidentally discovered adrenal masses (incidentalomas) remains controversial. Our objective was to describe the demographic and clinical characteristics of a series of patients with adrenal incidentalomas attended in several hospitals of Castilla-La Mancha, and their diagnostic and therapeutic management.Material and methodsData were obtained by reviewing the patients’ medical charts.ResultsA total of 270 patients were included (28.1% from Toledo, 25.9% from Albacete, 24.1% from Ciudad Real, 15.9% from Cuenca and 5.9% from Guadalajara). The mean age was 60.3 ± 12 and 53.3% were women. Overweight or obesity were found in 80.6%, hypertension in 55.8%, diabetes mellitus in 25.6%, impaired fasting glucose or impaired glucose tolerance in 15.6%, osteopenia in 31.5% and osteoporosis in 20.4%. These percentages were similar in patients with subclinical Cushing's syndrome. Diameter was less than 3 cm in 66% of the tumors, and more than 4 cm in 14.3%. Eighty-five percent of the tumors were detected by computed tomography. After a median follow-up of 28.8 months, 6% of nonfunctioning adenomas progressed to subclinical Cushing's syndrome, tumoral enlargement of more than 1 cm was found in 9.4% and a contralateral mass developed in 8.9%. Surgical adrenalectomy was performed in 14.4% of the patients.ConclusionsOur study confirms the favorable outcome in most patients with adrenal incidentalomas and contributes to a better understanding of this clinical entity.