Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes

In lipid bilayers, cholesterol facilitates the formation of the liquid-ordered phase and enables the formation of laterally ordered structures such as lipid rafts. While these domains have an important role in a variety of cellular processes, the precise atomic-level mechanisms responsible for chole...

Descripción completa

Detalles Bibliográficos
Autores: Martinez-Seara Monné, Hector, Rog, Tomasz, Karttunen, Mikko, Vattulainen, Ilpo, Reigada Sanz, Ramon
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/95997
Acceso en línea:https://hdl.handle.net/2445/95997
Access Level:acceso abierto
Palabra clave:Colesterol
Dinàmica molecular
Membranes cel·lulars
Bicapes lipídiques
Cholesterol
Molecular dynamics
Cell membranes
Lipid bilayers
Descripción
Sumario:In lipid bilayers, cholesterol facilitates the formation of the liquid-ordered phase and enables the formation of laterally ordered structures such as lipid rafts. While these domains have an important role in a variety of cellular processes, the precise atomic-level mechanisms responsible for cholesterol's specific ordering and packing capability have remained unresolved.