Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes
In lipid bilayers, cholesterol facilitates the formation of the liquid-ordered phase and enables the formation of laterally ordered structures such as lipid rafts. While these domains have an important role in a variety of cellular processes, the precise atomic-level mechanisms responsible for chole...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/95997 |
| Acesso em linha: | https://hdl.handle.net/2445/95997 |
| Access Level: | acceso abierto |
| Palavra-chave: | Colesterol Dinàmica molecular Membranes cel·lulars Bicapes lipídiques Cholesterol Molecular dynamics Cell membranes Lipid bilayers |
| Resumo: | In lipid bilayers, cholesterol facilitates the formation of the liquid-ordered phase and enables the formation of laterally ordered structures such as lipid rafts. While these domains have an important role in a variety of cellular processes, the precise atomic-level mechanisms responsible for cholesterol's specific ordering and packing capability have remained unresolved. |
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