Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers

Pérez-Lago, Laura; Machado, Marina; Gómez-Ruiz, María de Mar; Sola-Campoy, Pedro J.; Buenestado-Serrano, Sergio; de la Cueva-García, Victor Manuel; López Herranz, Marta; Andrés Zayas, Cristina; Sánchez-Arcilla, Ignacio; Flores-García, Rubén Francisco; López Fresneña, María Nieves; García de San José, Sonia; Catalán Alonso, Pilar; Muñoz García, Patricia Carmen; García de Viedma, Darío

Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers

COVID-19 vaccination has proven to be effective at preventing symptomatic disease but there are scarce data to fully understand whether vaccinated individuals can still behave as SARS-CoV-2 transmission vectors. Based on viral genome sequencing and detailed epidemiological interviews, we report a no...

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Detalles Bibliográficos
Autores:	Pérez-Lago, Laura, Machado, Marina, Gómez-Ruiz, María de Mar, Sola-Campoy, Pedro J., Buenestado-Serrano, Sergio, de la Cueva-García, Victor Manuel, López Herranz, Marta, Andrés Zayas, Cristina, Sánchez-Arcilla, Ignacio, Flores-García, Rubén Francisco, López Fresneña, María Nieves, García de San José, Sonia, Catalán Alonso, Pilar, Muñoz García, Patricia Carmen, García de Viedma, Darío
Tipo de recurso:	artículo
Fecha de publicación:	2022
País:	España
Institución:	Universidad Complutense de Madrid (UCM)
Repositorio:	Docta Complutense
Idioma:	inglés
OAI Identifier:	oai:docta.ucm.es:20.500.14352/120013
Acceso en línea:	https://hdl.handle.net/20.500.14352/120013
Access Level:	acceso abierto
Palabra clave:	61 COVID-19 SARS-CoV-2 Transmission Vaccination Nosocomial Genomics Ciencias Biomédicas 3299 Otras Especialidades Médicas

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spelling	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care WorkersPérez-Lago, LauraMachado, MarinaGómez-Ruiz, María de MarSola-Campoy, Pedro J.Buenestado-Serrano, Sergiode la Cueva-García, Victor ManuelLópez Herranz, MartaAndrés Zayas, CristinaSánchez-Arcilla, IgnacioFlores-García, Rubén FranciscoLópez Fresneña, María NievesGarcía de San José, SoniaCatalán Alonso, PilarMuñoz García, Patricia CarmenGarcía de Viedma, Darío61COVID-19SARS-CoV-2TransmissionVaccinationNosocomialGenomicsCiencias Biomédicas3299 Otras Especialidades MédicasCOVID-19 vaccination has proven to be effective at preventing symptomatic disease but there are scarce data to fully understand whether vaccinated individuals can still behave as SARS-CoV-2 transmission vectors. Based on viral genome sequencing and detailed epidemiological interviews, we report a nosocomial transmission event involving two vaccinated health care-workers (HCWs) and four patients, one of them with fatal outcome. Strict transmission control measures, as during the prevaccination period, must be kept between HCWs and HCWs-patients in nosocomial settings. IMPORTANCE COVID-19 vaccination has proven to be effective at preventing symptomatic disease. Although some transmission events involving vaccinated cases have also been reported, scarce information is still available to fully understand whether vaccinated individuals may still behave as vectors in SARS-CoV-2 transmission events. Here, we report a SARS-CoV-2 nosocomial transmission event, supported on whole genome sequencing, in early March 2021 involving two vaccinated HCWs and four patients in our institution. Strict transmission control measures between HCWs and HCWs - patients in nosocomial settings must not be relaxed, and should be kept as strictly as during the prevaccination period.American Society for MicrobiologyUniversidad Complutense de Madrid20222022-01-0520222022-01-05journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/120013reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1200132026-06-02T12:44:21Z
dc.title.none.fl_str_mv	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
title	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
spellingShingle	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers Pérez-Lago, Laura 61 COVID-19 SARS-CoV-2 Transmission Vaccination Nosocomial Genomics Ciencias Biomédicas 3299 Otras Especialidades Médicas
title_short	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
title_full	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
title_fullStr	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
title_full_unstemmed	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
title_sort	Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
dc.creator.none.fl_str_mv	Pérez-Lago, Laura Machado, Marina Gómez-Ruiz, María de Mar Sola-Campoy, Pedro J. Buenestado-Serrano, Sergio de la Cueva-García, Victor Manuel López Herranz, Marta Andrés Zayas, Cristina Sánchez-Arcilla, Ignacio Flores-García, Rubén Francisco López Fresneña, María Nieves García de San José, Sonia Catalán Alonso, Pilar Muñoz García, Patricia Carmen García de Viedma, Darío
author	Pérez-Lago, Laura
author_facet	Pérez-Lago, Laura Machado, Marina Gómez-Ruiz, María de Mar Sola-Campoy, Pedro J. Buenestado-Serrano, Sergio de la Cueva-García, Victor Manuel López Herranz, Marta Andrés Zayas, Cristina Sánchez-Arcilla, Ignacio Flores-García, Rubén Francisco López Fresneña, María Nieves García de San José, Sonia Catalán Alonso, Pilar Muñoz García, Patricia Carmen García de Viedma, Darío
author_role	author
author2	Machado, Marina Gómez-Ruiz, María de Mar Sola-Campoy, Pedro J. Buenestado-Serrano, Sergio de la Cueva-García, Victor Manuel López Herranz, Marta Andrés Zayas, Cristina Sánchez-Arcilla, Ignacio Flores-García, Rubén Francisco López Fresneña, María Nieves García de San José, Sonia Catalán Alonso, Pilar Muñoz García, Patricia Carmen García de Viedma, Darío
author2_role	author author author author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Universidad Complutense de Madrid
dc.subject.none.fl_str_mv	61 COVID-19 SARS-CoV-2 Transmission Vaccination Nosocomial Genomics Ciencias Biomédicas 3299 Otras Especialidades Médicas
topic	61 COVID-19 SARS-CoV-2 Transmission Vaccination Nosocomial Genomics Ciencias Biomédicas 3299 Otras Especialidades Médicas
description	COVID-19 vaccination has proven to be effective at preventing symptomatic disease but there are scarce data to fully understand whether vaccinated individuals can still behave as SARS-CoV-2 transmission vectors. Based on viral genome sequencing and detailed epidemiological interviews, we report a nosocomial transmission event involving two vaccinated health care-workers (HCWs) and four patients, one of them with fatal outcome. Strict transmission control measures, as during the prevaccination period, must be kept between HCWs and HCWs-patients in nosocomial settings. IMPORTANCE COVID-19 vaccination has proven to be effective at preventing symptomatic disease. Although some transmission events involving vaccinated cases have also been reported, scarce information is still available to fully understand whether vaccinated individuals may still behave as vectors in SARS-CoV-2 transmission events. Here, we report a SARS-CoV-2 nosocomial transmission event, supported on whole genome sequencing, in early March 2021 involving two vaccinated HCWs and four patients in our institution. Strict transmission control measures between HCWs and HCWs - patients in nosocomial settings must not be relaxed, and should be kept as strictly as during the prevaccination period.
publishDate	2022
dc.date.none.fl_str_mv	2022 2022-01-05 2022 2022-01-05
dc.type.none.fl_str_mv	journal article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://hdl.handle.net/20.500.14352/120013
url	https://hdl.handle.net/20.500.14352/120013
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.publisher.none.fl_str_mv	American Society for Microbiology
publisher.none.fl_str_mv	American Society for Microbiology
dc.source.none.fl_str_mv	reponame:Docta Complutense instname:Universidad Complutense de Madrid (UCM)
instname_str	Universidad Complutense de Madrid (UCM)
reponame_str	Docta Complutense
collection	Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score	15,812455

Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers

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