Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?

Pasteurized donor human milk (DHM) is the preferred alternative for infant nutrition when own mother's milk (OMM) is unavailable. Whether DHM is an efficient means for protecting preterm infants from oxidative stress remains unknown. We quantified a panel of oxidative stress biomarkers in urine...

Descripción completa

Detalles Bibliográficos
Autores: Parra-Llorca, A, Gormaz, M, Sanchez-Illana, A, Pineiro-Ramos, JD, Collado, MC, Serna, E, Cernada, M, Nunez-Ramiro, A, Ramon-Beltran, A, Oger, C, Galano, JM, Vigor, C, Durand, T, Kuligowski, J, Vento, M
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p3891
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/3891
Access Level:acceso abierto
Palabra clave:preterm infant
full enteral feeding
oxidative stress
donor human milk (DHM)
own mother's milk (OMM)
biomarkers
id ES_aa5e58ecce445c490a933f5f1a1f8a4f
oai_identifier_str oai:incliva.fundanetsuite.com:p3891
network_acronym_str ES
network_name_str España
repository_id_str
spelling Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?Parra-Llorca, AGormaz, MSanchez-Illana, APineiro-Ramos, JDCollado, MCSerna, ECernada, MNunez-Ramiro, ARamon-Beltran, AOger, CGalano, JMVigor, CDurand, TKuligowski, JVento, Mpreterm infantfull enteral feedingoxidative stressdonor human milk (DHM)own mother's milk (OMM)biomarkersPasteurized donor human milk (DHM) is the preferred alternative for infant nutrition when own mother's milk (OMM) is unavailable. Whether DHM is an efficient means for protecting preterm infants from oxidative stress remains unknown. We quantified a panel of oxidative stress biomarkers in urine samples from preterm infants (<= 32 weeks of gestation and a birth weight <= 1500 g) receiving >= 80% of feeding volume as either DHM or OMM. The noninvasive in vivo assessment of oxidative stress showed no statistically significant difference between both groups at the time when full enteral nutrition (150 mL/kg body weight) was achieved and until hospital discharge. In addition, the changes of urinary biomarker levels with time were assessed. This is the first longitudinal study on oxidative stress levels in preterm infants fed with DHM in comparison with OMM. There is no statistically significant difference in urinary oxidative stress levels of preterm infants from both groups indicating that despite the effects of pasteurization, DHM is a valid alternative when OMM is not available. Based on the results, we raise the hypothesis that pasteurized DHM protects preterm infants from oxidative stress as good as OMM, and consequently, its use could prevent oxidative stress-related diseases. Antioxid. Redox Signal. 31, 791-799.MARY ANN LIEBERT, INC2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://incliva.portalinvestigacion.com/publicaciones/3891ANTIOXIDANTS & REDOX SIGNALINGISSN: 15230864ISSNe: 15577716reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAinstname:INCLIVAInglésinfo:eu-repo/semantics/openAccessoai:incliva.fundanetsuite.com:p38912026-06-07T16:35:31Z
dc.title.none.fl_str_mv Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
title Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
spellingShingle Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
Parra-Llorca, A
preterm infant
full enteral feeding
oxidative stress
donor human milk (DHM)
own mother's milk (OMM)
biomarkers
title_short Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
title_full Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
title_fullStr Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
title_full_unstemmed Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
title_sort Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress?
dc.creator.none.fl_str_mv Parra-Llorca, A
Gormaz, M
Sanchez-Illana, A
Pineiro-Ramos, JD
Collado, MC
Serna, E
Cernada, M
Nunez-Ramiro, A
Ramon-Beltran, A
Oger, C
Galano, JM
Vigor, C
Durand, T
Kuligowski, J
Vento, M
author Parra-Llorca, A
author_facet Parra-Llorca, A
Gormaz, M
Sanchez-Illana, A
Pineiro-Ramos, JD
Collado, MC
Serna, E
Cernada, M
Nunez-Ramiro, A
Ramon-Beltran, A
Oger, C
Galano, JM
Vigor, C
Durand, T
Kuligowski, J
Vento, M
author_role author
author2 Gormaz, M
Sanchez-Illana, A
Pineiro-Ramos, JD
Collado, MC
Serna, E
Cernada, M
Nunez-Ramiro, A
Ramon-Beltran, A
Oger, C
Galano, JM
Vigor, C
Durand, T
Kuligowski, J
Vento, M
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv preterm infant
full enteral feeding
oxidative stress
donor human milk (DHM)
own mother's milk (OMM)
biomarkers
topic preterm infant
full enteral feeding
oxidative stress
donor human milk (DHM)
own mother's milk (OMM)
biomarkers
description Pasteurized donor human milk (DHM) is the preferred alternative for infant nutrition when own mother's milk (OMM) is unavailable. Whether DHM is an efficient means for protecting preterm infants from oxidative stress remains unknown. We quantified a panel of oxidative stress biomarkers in urine samples from preterm infants (<= 32 weeks of gestation and a birth weight <= 1500 g) receiving >= 80% of feeding volume as either DHM or OMM. The noninvasive in vivo assessment of oxidative stress showed no statistically significant difference between both groups at the time when full enteral nutrition (150 mL/kg body weight) was achieved and until hospital discharge. In addition, the changes of urinary biomarker levels with time were assessed. This is the first longitudinal study on oxidative stress levels in preterm infants fed with DHM in comparison with OMM. There is no statistically significant difference in urinary oxidative stress levels of preterm infants from both groups indicating that despite the effects of pasteurization, DHM is a valid alternative when OMM is not available. Based on the results, we raise the hypothesis that pasteurized DHM protects preterm infants from oxidative stress as good as OMM, and consequently, its use could prevent oxidative stress-related diseases. Antioxid. Redox Signal. 31, 791-799.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://incliva.portalinvestigacion.com/publicaciones/3891
url https://incliva.portalinvestigacion.com/publicaciones/3891
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MARY ANN LIEBERT, INC
publisher.none.fl_str_mv MARY ANN LIEBERT, INC
dc.source.none.fl_str_mv ANTIOXIDANTS & REDOX SIGNALING
ISSN: 15230864
ISSNe: 15577716
reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname:INCLIVA
instname_str INCLIVA
reponame_str r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416157094608896
score 15.81155

Similares en LA Referencia